细胞毒性T细胞(Cytotoxic T Cells,简称Tc细胞)是适应性免疫系统的关键组成部分,主要通过直接杀伤受感染或癌变的细胞来维持
Effector CD8+ T cell phenotypes Naive CD8+ can differentiate into multiple effector phenotypes with different roles [4]. Effector phenotypes are characterized by high cytotoxic ability and production of cytokines. The killing of target cells is fulfilled by CTLs that ...
the direct killing of cells that are infected (particularly with viruses), cancerous or damaged in other ways. They express the glycoprotein CD8, as well as T cell receptors that recognize antigenic peptides presented by MHC class I molecules. There are two effector phenotypes: TC1 and TC2....
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The mechanism of the lysis of target cells by cytotoxic T-cells (Tc) is still obscure; there is no evidence for transfer of material from the Tc and prior to lysis, despite intimate contact, the plasma membranes of both types of cell appear to remain intact. The effects on the target ...
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Monoclonal antibodies specific for either T3 and Ti are able to elicit a variety of T-cell responses such as lymphokine production, mitogenesis and cytotoxicity. For example, human Tc cells lyse anti-T3-expressing hybridoma cells, but not cells of other specificity, presumably because anti-T3 ...
Noun1.cytotoxic T cell- T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it CD8 cell,CD8 T cell,killer cell,killer T cell T cell,T lymphocyte- a small lymphocyte developed in the thymus; it orchestrates th...
The CD8+ T cells, also known as Cytotoxic T cells (TCcells), are a type of T cells that kill cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways. Most cytotoxic T cells express T-cell receptors (TCRs) that can recognize ...