the direct killing of cells that are infected (particularly with viruses), cancerous or damaged in other ways. They express the glycoprotein CD8, as well as T cell receptors that recognize antigenic peptides presented by MHC class I molecules. There are two effector phenotypes: TC1 and TC2....
cytotoxic/ saɪtə'tɑksɪk/ 释义adj. [细胞] 细胞毒素的 例句Objective To study the killing ability of tumor specific cytotoxic T cells on target tumor cells.目的在于研究肿瘤特异性细胞毒T细胞对其靶细胞的杀伤作用。 Cell英 /sel/ 美 /sel/ ...
Murine cytotoxic T-cell (Tc cell) responses to various antigens are controlled by immune response genes (Ir) mapping in the major histocompatibility complex (H-2). Both helper T cells, controlled by I region-coded genes, and Tc cells, controlled by K/D antigens, are necessary for a ...
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1、细胞毒T细胞（cytotoxic T cell）：消灭受感染的细胞。这些细胞的功能就像一个“杀手”或细胞毒素，因为它们可以对产生特殊抗原反应的目标细胞进行杀灭。细胞毒T细胞的主要表面标志是CD8，也被称为杀手T细胞。2、辅助T细胞（helper T cell）在免疫反应中扮演中间过程的角色：它可以增生扩散来激活其它类型...
cytotoxic T cell_动物学行业词汇 细胞毒性T[淋 巴]细胞 cytotoxic T cell_生物学行业词汇 细胞毒性T 细胞 又称:细胞毒性T 细胞(TC ) cytotoxic T cell词源英文解释 The first known use of cytotoxic T cell was in 1975 cytotoxic T cell医学词典英英释义 ...
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Exposure of CD4 naïve cells to TGF-β alone (e.g., in the absence of IL-6) will drive the differentiation toT regulatory cells(Treg cells; seeFig. 55.2).Treg cellsare a population of T cells that act as powerful suppressors of the T cell-mediated immune response and of self-reactive...
Table 1. CD8+T cell effector phenotype and function. TypePolarizing cytokinesin vitroTranscription factorsEffector moleculesFunction Tc1IL-2, IL-12T-bet, BLIMP1, Id2, IRF-4IFNγ, TNFα, granzymes, perforinImmunity against intracellular pathogens and tumors ...