In the disease context, over activation of IL-36 has now been associated with many inflammatory diseases including Psoriasis and inflammatory bowel diseases, with roles in cancer also now being investigated. This review summarises the current knowledge of IL-36 biology, its role in inflammatory ...
Cytokines in inflammatory bowel disease AL.C. MOLDOVEANU1,3, M. DICULESCU2,3, CARMEN FIERBIN?EANU BRATICEVICI1,3 1 Internal Medicine II and Gastroenterology Clinic, University Hospital Bucharest 2 Department of Gastroenterology, Fundeni Clinical Institute, Bucharest 3 “Carol Davila” University ...
Cytokines have a crucial role in the pathogenesis of inflammatory bowel diseases (IBDs), such as Crohn's disease and ulcerative colitis, where they control multiple aspects of the inflammatory response. In particular, the imbalance between pro-inflammatory and anti-inflammatory cytokines that occurs ...
The production of cytokines in human skin in vivo has been investigated and found to be more selective than studies in vitro have suggested. Thus, stratum corneum samples from the skin lesions of psoriasis contain interleukin 8 (IL-8)-like material, but assay for a range of other compounds ...
McGeer PL, McGeer EG. The inflammatory system of brain: implications for therapy of Alzheimer and other neurodegenerative disorders. Brain Res Rev 1995 Sep; 21(2): 195–218 PubMedCASGoogle Scholar Mrak RE, Sheng JG, Griffin WST. Glial cytokines in Alzheimer’s disease — review and pathogeni...
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The immune system is poised like a fulcrum to respond quickly to challenge by infectious agents, but can produce excess inflammatory signals or excess suppressive signals when out of balance. During the past year, significant progress has been made in our understanding of how certain pathogens promo...
Inflammatory cytokines in vascular dysfunction and vascular disease. The vascular inflammatory response involves complex interaction between inflammatory cells (neutrophils, lymphocytes, monocytes, macrophages), endothelial ... AH Sprague,RA Khalil - 《Biochemical Pharmacology》 被引量: 1207发表: 2009年 Syner...
This review is focused on the inflammatory processes that develop diabetic nephropathy and on the new therapeutic approaches with anti-inflammatory effects for the treatment of chronic kidney disease in the setting of diabetic nephropathy. 展开
Inflammatory Cytokines in Acute Ischemic Stroke Three major cytokines, namely, tumor necrosis factor (TNF-卤), interleukin (IL)-1, and IL-6 are produced by cultured brain cells after various stimuli such... A Tuttolomondo,DD Raimondo,RD Sciacca,... - 《Current Pharmaceutical Design》 被引...