Although most cytokines have a predictable role in either amplifying or attenuating inflammation in IBD, a few cytokines have shown a dual function in the inflammatory state of the intestine. Some of these dual-faced cytokines are also involved in mucosal anti-microbial defense pathways, particularly...
By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various cytokines have been documented to play important regulatory roles in determining cardiac function under both physiological and pathophysiological conditions. Several cytokines including TNF-α, TGF-β, and different...
We propose that TGF-β1 acts as a negative regulator of mast cell function, in part by decreasing FcεRI expression. G Gomez,CD Ramirez,J Rivera,... - 《Journal of Immunology》 被引量: 281发表: 2005年 TGF- 1 Inhibits Mast Cell Fc RI Expression The related cytokines, TGF-β2 and ...
Finally, various cytokines, such as tumor necrosis factor-α, IL-6, tumor necrosis factor-like cytokine 1A, and death receptor, 3 demonstrate dichotomous roles with mucosa-protective function in acute injury but proinflammatory effects during chronic inflammation. The role of cytokines in mucosal ...
Cytokine-Induced Inflammation in the Central Nervous System Revisited Cytokines play an essential role as mediators of the immune response. They usually function as part of a network of interactive signals that either activat... JA Martiney,C Cuff,M Litwak,... - 《Neurochemical Research》 被引...
which can accelerate the restenosis process. Other cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1) in the initial inflammation inhibit restenosis by affecting insulin-like growth factor binding proteins (IGFBPs). Considering the synergism effects of inflammatory cytokines...
View in ScopusGoogle Scholar [49] Y.M. Báez-Santos, S.E. St John, A.D. Mesecar The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds Antivir. Res., 115 (2015), pp. 21-38 View in ScopusGoogle Scholar [50] A.M. Zaki, S. van...
Inflammatory cytokines are related to cognitive function and psychiatric disorders in patients with several diseases. However, few relevant studies have be... R Li,W Fan,D Li,... 被引量: 0发表: 2022年 Pro-inflammatory cytokine level and neutrophil count in acute ischemic stroke Background: Pro...
and immune escape of the endometriotic lesions. In this review, we provide an overview of the expression, origin, function and regulation of anti-inflammatory cytokines in endometriosis, with brief discussion and perspectives on their future clinical implications in the diagnosis and therapy of the di...
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