抗体名:Cytokine Receptor Common beta-Chain Antibody 靶点:详见说明书 宿主:详见说明书 用途:公司产品仅用于科研 应用范围:公司产品仅用于科研 纯度:详见说明书 % 产地:进口、国产 品牌:谷研 货号:GOYK98149 用途:仅用于科研 亚型:IgG 是否单克隆:是
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Cytokine Receptor Common beta-Chain Antibody| 基本信息更多信息 中文名称: 中文同义词: 英文名称:Cytokine Receptor Common beta-Chain Antibody 英文同义词:Cytokine Receptor Common beta-Chain Antibody CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 ...
beta receptor, beta-adrenergic receptor, beta-adrenoceptor - receptors postulated to exist on nerve cell membranes of the sympathetic nervous system in order to explain the specificity of certain agents that affect only some sympathetic activities (such as vasodilation and increased heart beat) 2. rec...
The common γ-chain cytokine receptor: tricks-and-treats for T cells. Cell Mol Life Sci. 2016; 73:253-69. https://doi.org/10.1007/s00018- 015-2062-4Waickman, A. T., Park, J. Y. & Park, J. H. The common g-chain cytokine receptor: tricks-and-treats for T cells. Cell Mol ...
the common beta chain is shared by IL-3, IL-5 and GM-CSF, and the common gamma chain is shared by IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21). These shared receptor elements underlie the fact that cytokines can engage both in high-affinity binding to their own “private” ...
J. The common cytokine receptor gamma chain family of cytokines. Cold Spring Harb. Perspect. Biol. 10, a028449 (2018). Article PubMed PubMed Central Google Scholar Spolski, R., Li, P. & Leonard, W. J. Biology and regulation of IL-2: from molecular mechanisms to human therapy. Nat...
et al. The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2, 331–339 (1995). Article Google Scholar Berraondo, P. et al. Cytokines in clinical cancer immunotherapy. ...
Downstream components of the cytokine signaling cascades are also being explored as targets for drug development. Gain-of-function mutations in theJAK2(hot spot V617F) andMPLgenes, the latter of which encodes the thrombopoietin receptor, are common in myeloproliferative neoplasms, and the selective ...
The role of the common cytokine receptor gamma-chain in regulating IL-2-dependent, activation-induced CD8+ T cell death. IL-2-dependent, activation-induced T cell death (AICD) plays an important role in peripheral tolerance. Using CD8+ TCR-transgenic lymphocytes (2C), we inve... Z Dai,A...