Finally, computer searches identified homology between the mousegene andand, two genes identified inthat negatively regulate the-cyclic AMP pathway. These findings provide important new insights into the possible function of thegene.Arthur M. Buchberg...
The cyclic AMP pathway. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148.[3]. Aronoff DM, et, al. Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. J Interferon ...
Cyclic AMP, the product of the membrane-boundenzyme,adenylate cyclase, was the first intracellular second messenger identified (Sutherland and Rall, 1958). Thecyclic AMPsignaling pathwayis highly conserved and is involved in a multitude of physiological functions (Hanoune and Defer, 2001). MultipleG...
Related to cyclic AMP:cyclic GMP,G protein cyclic AMP n.Abbr.cAMP A cyclic nucleotide of adenosine that is produced inside cells in response to external stimuli, such as hormones, and triggers various biochemical pathways within the cell. ...
This has significant physiological relevance since the pathway is strongly implicated in . Finally, we show that the repressor is inducible in the line upon activation of the and of the activator CREB. 展开 关键词: cAMP CREM CREB liver regeneration proliferation early response ...
Classification of the Triozidae from Korea The cyclic AMP pathway is a major regulator of thyrocyte function and proliferation and, predictably, its inappropriate activation is associated with a sub... YJ Kwon - 《Oncogene》 被引量: 3发表: 1981年 加载更多站内活动 0关于...
(IFN) pathway. In vitro, fibroblasts, macrophages, and dendritic cells isolated from cGAS knockout (cGAS-/-) mice do not produce type I IFNs following DNA transfection or DNA virus infection. Similarly, cells containing a frame-shift mutation in the cGAS locus fail to mount an immune ...
3',3'-cyclic GMP-AMP, Cyclic GMP-AMP, c GAMP 靶点(Target) STING 通路(Pathway) Immunology/Inflammation--STING CAS号(CAS NO.) 849214-04-6 分子式(Formula) C20H24N10O13P2 分子量(Molecular Weight) 674.41 外观(Appearance) 粉末 纯度(Purity) ...
In conclusion, this study demonstrates that mouse oocytes can generate ATP from AMP via the adenosine salvage pathway, and cAMP elevation alters adenine nucleotide metabolism and may provide AMP for energy production via the adenosine salvage pathway during the energetically demanding process of meiotic ...
Thyrotropin (TSH), via a cyclic AMP (cAMP)-dependent pathway, induces cytoplasmic retractions, proliferation, and differentiation expression in dog thyroid... S Dremier,V Pohl,C Poteet-Smith,... - 《Molecular & Cellular Biology》 被引量: 344发表: 1997年 Selective hormonal activation of cyclic...