As such, cyclic AMP signaling has become an attractive target for drug development for the treatment of a large variety of diseases. Cyclic AMP Pathway cAMP, as an essential messenger involved in regulating metabolism and biological functions in cells, transfers information regarding cellular status...
1997. Cyclic AMP signaling pathway and cellular prolif- eration: induction of CREM during liver regeneration. Oncogene 14:1601- 1606.Servillo, G., Penna, L., Foulkes, N. S., Magni, M. V., Della Fazia, M. A., and Sassone-Corsi, P. (1997). Cyclic AMP signalling pathway and ...
Cyclic AMP, the product of the membrane-boundenzyme,adenylate cyclase, was the first intracellular second messenger identified (Sutherland and Rall, 1958). Thecyclic AMPsignaling pathwayis highly conserved and is involved in a multitude of physiological functions (Hanoune and Defer, 2001). MultipleG...
Cyclic AMP signaling. J Cell Sci. 2001 Jun;114(Pt 11):1971-2.[2]. Paolo Sassone-Corsi, et al. The cyclic AMP pathway. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148.[3]. Aronoff DM, et, al. Short communication: differences between macrophages and dendritic cells in ...
2006. Cross talk between a fungal blue-light perception system and the cyclic AMP signaling pathway. Eukaryot Cell, 5(3): 499–506. Google Scholar ... Susanne,Zeilinger,Markus,... - 《Gene Regulation & Systems Biology》 被引量: 83发表: 2007年 Cross-talk between light and glucose regulatio...
The cyclic GMP–AMP synthase (cGAS)–STING pathway is a central component of the cell-autonomous innate immune system in animals1,2. The cGAS protein is a sensor of cytosolic viral DNA and, upon sensing DNA, it produces a cyclic GMP–AMP (cGAMP) signalli
While we have yet to determine the exact mechanisms of the increased cAMP or PKA activity, we have clearly identified a novel signaling pathway for EV-induced cAMP signaling. CRediT authorship contribution statement Aritra Bhadra: Investigation, Visualization, Writing – review & editing. April K. ...
1. Sun, L., et al., Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.Science, 2013. 339(6121): p. 786-91.2. Wu, J., et al., Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.Science, 2013....
Related to cyclic AMP:cyclic GMP,G protein cyclic AMP n.Abbr.cAMP A cyclic nucleotide of adenosine that is produced inside cells in response to external stimuli, such as hormones, and triggers various biochemical pathways within the cell. ...
Several neuroendocrine control systems are prominently controlled by G-protein coupled receptors that activate the cAMP signal transduction pathway. The discovery of multiple genes that encode the molecular machinery of cAMP metabolism has revolutionized our knowledge of cAMP mediated processes. This perhaps...