To date, no curative treatment is available for MSA. Recent results of neuroprotective and -restorative trials have provided some hope for future advances. Considerations for future clinical trials are also discussed in this review.doi:10.1002/mdc3.12145Santiago...
Increasing recognition and emerging therapies argue for dedicated clinical trials in chronic myelomonocytic leukemia Article26 June 2021 Introduction A better understanding of the pathobiology of acute myeloid leukemia (AML) has accelerated the progress of translational-clinical research and therapeutic applicati...
2024. Both experimental and clinical studies were included. The titles and abstracts were screened for key terms, such as ‘Multiple sclerosis’, ‘Experimental Allergic Encephalomyelitis’, ‘Treatment options’, ‘Clinical trials’, and ‘Treatment targets’. Further...
chemotherapy combined with α-PD-1/PD-L1 has become a standard-of-care option for some cancer patients, and there are hundreds of ongoing clinical trials exploring the efficacy and safety
In summary, as of today, no clinical trials have demonstrated a benefit of intensifying the conditioning regimen in MDS patients. Careful pharmacokinetic (PK)-guided intravenous busulfan (Bu) strategies have not highlighted differences in OS between RIC and MAC [45,46]. Because MDS is usually dia...
Efficacy and safety of Xuebijing injection (a Chinese patent) for sepsis: a meta-analysis of randomized controlled trials. J Ethnopharmacol. 2018;224:512–21. Article PubMed Google Scholar Qi F, Liang ZX, She DY, Yan GT, Chen LA. A clinical study on the effects and mechanism of xue...
Home monitoring via patient self-measurements has been shown to be a valuable adjunct of modern teleophthalmology [142,143]. In addition to reducing the need for clinical visits, it facilitates the collection of high quality data in a personal setting that can guide targeted management [143]. ...
(7.0–95.0) and it was more difficult to control the disease at that stage.55 This is a retrospective study, but demonstrates the need for well-designed clinical trials to answer these questions, espe- cially given our ability to identify patients at an early stage with the use of ...
Effect of amiodarone therapy on mortality in patients with left ventricular dysfunction and asymptomatic complex ventricular arrhythmias: Argentine pilot study of sudden death and amiodarone (EPAMSA). Am Heart J 1995; 130: 494–500 Article PubMed CAS Google Scholar Doval HC, Nul DR, Grancelli ...
Central neuropathic pain is caused by a disease or lesion of the brain or spinal cord. It is difficult to predict which patients will develop central pain