method(BMD).PCR,genecloningandDNAsequencingwerecarriedoutforESBLsgenotyping.Thesensitiverateofthe45 bacteriatomeropenemwas100%.rheresistantrateofESBLs—producingisolatesagainstAMP.KAN,NET,SMX,CTX, CRO.CFwasabove64%.41strainsproducedCTX—MgenotypeESBLs,mostofwhichwasCTX—M-14type,nextwasCTX—M一28. Key...
Conclusion: A significant relation between CTX-M gene and virulence factors was determined. Hence, surveillance and proper control strategies are essential to prevent the distribution virulent and drug-resistant E. coli. Although phosphomycin was found to be effective in eradicating extended spectrum 尾...
CTX—M encodinggene and study the epidemiologicalaspect of CTX-M-producing isolates. MethodsAtotalof254clinicalisolates ofmultidrug resistant gram—negative bacilliwerecollectedfromOctober2004to July 2005. ESBL—producing isolateswereconfirmed by means ofphenotypic confirmatory testsasrecommended by theCLSI/NCC...
FuL,PelicanoH,LiuJ,eta1.Thecircadiangenepailod2playsan importantroleintumorsuppressionandDNAdamageresponscin vivo口].Cell,2002,111(I):41—5O. 6 FilipskiE,LiXM,LeviF.Disruptionofcircadiancoordinationand malignantgrowth[J].CancerCausesControl,2006。17(4):5O9— ...
PCR, gene cloning and DNA sequencing were carried out for ESBLs genotyping. The sensitive rate of the 45 bacteria to meropenem was 100%. The resistant rate of ESBLs-producing isolates against AMP, KAN, NET, SMX, CTX,CRO, CF was above 64%. 41 strains produced CTX-M genotype ESBLs, ...
[ 结论] CTX—M 一15基因是大肠埃希菌和肺炎克雷伯菌对头孢他啶耐药的主要机制,建议临床合理使用抗生素,避免引起流行。关键词:CTX—M 一15;头孢他啶耐药;大肠埃希菌;肺炎克雷伯茵中图分类号:R378.21文献标志码:A文章编号:1671—7295( 2012) 05—0495—04CTX—M 一15genedetected i n ceftazi di m e—...
CTX Acronyms Wikipedia CTX Abbreviation forcyclophosphamide. Farlex Partner Medical Dictionary © Farlex 2012 CYP27A1 A gene on chromosome 2q33-qter that encodes a member of the cytochrome P450 superfamily of enzymes, which catalyse reactions involved in drug metabolism and synthesis of cholesterol, ...
环磷酰胺(Cyclophosphamide,CTX)是进入人体内被肝脏或肿瘤内存在的过量的磷酰胺酶或磷酸酶水解,变为活化作用型的磷酰胺氮芥而起作用的氮芥类衍生物。抗瘤谱广,是第一个所谓“潜伏化”广谱抗肿瘤药,对白血病和实体瘤都有效。 本品在体外无活性,主要通过肝脏P450酶水解成醛磷酰胺再运转到组织中形成磷酰胺氮芥而发挥作...
据有关报道,CTX-M型和TEM型或SHV型的同源性较低,仅为40%[2]。目前发现的的CTX-M型ESBLs种类超过107种,根据其氨基酸序列的差异(大于94%的相同序列认为是一个群,小于90%的相同序列认为是不同的群)分为5个群[3]:CTX-M-1 群包括 CTX-M-1、CTX-M-3、CTX-M-10、CTX-M-12、CTX-M-15、FEC-1、...
四川大学硕士学位论文肠杆菌科产CTX-M型超广谱β-内酰胺酶细菌的研究姓名:***学位级别:硕士专业:内科学(感染性疾病)指导教师:**建20030426四川大学华西医学中心硕士学位论文肠杆菌科产CTX-M型超广谱p一内酰胺酶细菌的研究硕士研究生:蔡琰导师:**建教授指导教师:**菊副教授冯萍副教授陈文昭副主任技师【摘要】目的...