CTX-M geneBackground and objective Today, bacterial resistance is one of the greatest medical challenges and it annually serves a huge amount of public and private investments since late or false diagnosis enda
银川产超广谱β-内酰胺酶菌株CTX-M型耐药基因的分布 摘要:为了了解银川市部分医院临床分离的产超广谱β-内酰胺酶(ESBLs)大肠埃希氏菌和肺炎克雷伯菌中CTX-M型ESBLs基因分布情况,采用微量肉汤法测定分离自宁夏地区两家医院的45株产ESBLs的大肠埃希氏菌和肺炎克雷伯菌对10种抗菌药物的最低抑菌浓度,通过聚合酶链反应...
CTX—M encodinggene and study the epidemiologicalaspect of CTX-M-producing isolates. MethodsAtotalof254clinicalisolates ofmultidrug resistant gram—negative bacilliwerecollectedfromOctober2004to July 2005. ESBL—producing isolateswereconfirmed by means ofphenotypic confirmatory testsasrecommended by theCLSI/NCC...
FuL,PelicanoH,LiuJ,eta1.Thecircadiangenepailod2playsan importantroleintumorsuppressionandDNAdamageresponscin vivo口].Cell,2002,111(I):41—5O. 6 FilipskiE,LiXM,LeviF.Disruptionofcircadiancoordinationand malignantgrowth[J].CancerCausesControl,2006。17(4):5O9— ...
1.METHODS The antimicrobial susceptibility test on ESBLs KPN which we have known its phenotype was conducted, then the CTX-M gene was amplified by polymerase chain reaction and detected.结果14株产ESBLs肺炎克雷伯菌药敏结果一致,耐三代头孢和耐酶抑制剂,均检出CTX-M基因。 2.Methods The CTX-M ge...
Recently, a blaCTX-M-10 gene (CTX-M-9 group) was detected within an original genetic context, associated with phage-related sequences (Fig. 2), suggesting that additional types of mobile element might be involved in the mobilisation of blaCTX-M genes. Download: Download full-size image ...
[ 结论] CTX—M 一15基因是大肠埃希菌和肺炎克雷伯菌对头孢他啶耐药的主要机制,建议临床合理使用抗生素,避免引起流行。关键词:CTX—M 一15;头孢他啶耐药;大肠埃希菌;肺炎克雷伯茵中图分类号:R378.21文献标志码:A文章编号:1671—7295( 2012) 05—0495—04CTX—M 一15genedetected i n ceftazi di m e—...
The results showed that the combined application of Mesona chinensis Benth.- containing serum and antimicrobial agents had antibacterial activity against the fosA3 gene-carr^^ing and CTX-M-producing E. coli strain, and the inhibitor^^ effects of the selected antibacterial agents including ...
Prevalence of clinically isolated Escherichia coli producingCTX-M-type β-lactamases in Peking Union Medical College Hospital; CTX-M酶在北京协和医院临床分离大肠埃希菌中的流行 2) CTX-M gene CTX-M型基因 3) CTX-M-type ESBLs CTX-M型超广谱β-内酰胺酶 ...
Methods The CTX-M gene and the mutant CTX-M gene were obtained using Polymerase Chain Reaction (PCR). 结果酶切鉴定和DNA测序鉴定表明CTX-M型酶的原核重组表达载体及其突变表达载体构建成功,转化大肠埃希菌JM109后,发现含野生型CTX-M基因的重组菌其酶活性与来源菌株相近,而含突变型CTX-M基因的重组菌未检...