Cryo electron microscopy, cryo EM enables analysis of biological samples at cryogenic conditions, producing high-resolution 3D data of proteins, cells, and more.
Cryo-EM instruments and techniques Cryo-transmission electron microscopes Achieve unparalleled resolution with Thermo Scientific cryo-TEMs. Our full cryo-TEM portfolio features state-of-the-art technology with a range of automation features designed to extend accessibility and ease-of-use. Meet the cry...
Cryo-EM is being led by the technology and innovation behind Gatan's direct detection cameras (K3®and K2®). The efficient frontier of resolutionAdvantagesWorkflow for cryo-EM What is single-particle cryo-EM? 1.54 Å resolution cryo-EM structure of apoferritin. Data courtesy of Kato T,...
This advancement was made possible by the evolution of cryo-EM technology, including the new 200 kVThermo Scientific Glacios 2 Cryo-TEM, which delivered early and impressive results after it wasannounced in October 2022. In March 2024, Themo Fisher Scientific introduced an optional low-energy-spre...
Cryo-EM technology has developed to the point of high-throughput structure determination of biological macromolecules embedded in vitreous ice. Nonetheless, challenging targets need extensive sample screening, often of many cryo-EM sample grids prepared under various conditions. We have designed and made...
Cryo EM research innovations in 2020 Innovations in cryo-electron microscope technology are bringing structural biology into a new era, and 2020 was packed with significant breakthroughs and discoveries. With the year coming to a close, it’s exciting to see our customers recog...
Whether you are new to cryo-electron microscopy (cryo-EM) or have years of experience with this technology, securing funding can be demanding, time-consuming, and stressful. Our team is here to help! This funding support center contains several resources...
Cryo-EM in biosafety labs Our decontamination solution enables pathogen research and comprehensive instrument service in higher biosafety-level containment facilities (e.g. BSL3). Learn more For Research Use Only. Not for use in diagnostic procedures....
Resolving these issues, among others, cryo-EM could become a more versatile and influential technology in structural biology, potentially addressing research questions and aiding the growth of methodologies as the field advances49. Methods Details of comparing the performance of particle sorting algorithms...
(FIB) to thin cells and allows for electron tomography (ET). The process is similar to a CT scan at the cellular level and results in unprecedented resolution that can be applied to both cell biology and cancer research. In theory, this technology could be applied to a whole tumor ...