Cryo-EM reconstruction and modelling Full size image Fold of the fibril protein Full size image Full size image Analysis of the sequence of TTR-V30M with computational tools31,32,33,34,35reveals several highly amyloidogenic segments within the fibril core, while residues Gly1-Cys10 and Ala36-...
a, Overview of cryo-EM data collection and image-processing procedure (see Methods). b, Representative micrograph of the α1β3γ2L–Mb38–nanodisc complex obtained using the Falcon3 detector and Volta phase plate. c, Representative 2D class averages for downscaled data (box size of 240 ...
Box size (pixel) 192 Pixel size (Å) 1.13 Symmetry C3 Map resolution (Å) 4.6 FSC threshold 0.143 Map sharpening B-factor (Å2) −320 EMDB code EMD-10325 The cryo-EM map of the outer capsid clearly shows the organization of the pseudo-hexagonal capsomers (Fig. 2, A and B). ...
Download:Download full-size image Figure 5. Myristoyl Group of the Primed VP5 in the ISVP (A) Positions of three myristoyl groups (red balls) near the base of the VP5 trimer. See alsoMovie S4. (B) Cryo-EM density (gray mesh) of the base region in Figure 5A (red box), superimpose...
Simplify cryo grid box handling with these easy-to-use tweezers. Specially designed to grip the box’s central screw, rather than its sides 价格说明 价格:商品在爱采购的展示标价,具体的成交价格可能因商品参加活动等情况发生变化,也可能随着购买数量不同或所选规格不同而发生变化,如用户与商家线下达成协议...
但是cryo-EM和其他材料电镜不同的是,我们希望能够移动和倾斜样品。因此我们需要个sample stage,而且必须非常精确。 可以在三维(XYZ)方向移动。需要非常精确,尤其是Z方向的移动关系到focus; 能够进行Tilt(cryo-ET常用),具有测角器(goniometer)。而且需要保证on-axis rotation; 在液氮温度下运行,收集高分辨率数据时其...
Down syndrome (DS) is a common genetic condition caused by trisomy of chromosome 21. Among their complex clinical features, including musculoskeletal, neurological, and cardiovascular disabilities, individuals with DS have an increased risk of developing
Foam+ Aluminium Box Best Cryo Freezing Machine Cryoplus 5 in one Thermal Cryo EMS Shock Cryo Freezing Star T-Shock Bodyslim Cryotherapy Machine Selling Units: Single item Single package size: 55X65X45 cm Single gross weight: 40.000 kg
Customized foundational image segmentation models for picking protein particles in cryo-EM images - jianlin-cheng/CryoSegNet
CryoSPARC is the state-of-the-art platform used globally for obtaining 3D structural information from single particle cryo-EM data. The cryoSPARC platform enables automated, high quality and high-throughput structure discovery of proteins, viruses and m