Abstract. Translational research on the Cre/loxP recombination system focuses on enhancing its specificity by modifying Cre/DNA interactions. Despite exten
13、ral investigators have re-emphasized on the importance of creating genomic acceptor sites for foreign genes by insertion of pairs of hetero-specific lox sites to appropriate gene loci 11.Cre/lox site-specific recombination system is a high崔文涛等:一种利用Cre/loxP系统进行标记基因删除与靶基因置...
Summary Cell type-specific genetic modification using the Cre/loxP system is a powerful tool for genetic analysis of distinct cell lineages. Because of the exquisite specificity of Vasa expression (confined to the germ cell lineage in invertebrate and vertebrate species), we hypothesized that a Vasa...
一种利用Cre_loxP系统进行标记基因删除与靶基因置换的细胞模型研究_英文_.pdf ResearchPapers 研究报告 生物化学与生物物理进展 ProgressinBiochemistryandBiophysics 2008,35(6):650~660 AModelStudy:SimulationofMarkerGene DeletionandTargetGeneReplacement * MediatedbyCre/loxSysteminCellLine 1,2) 1) 1) 1) 1) ...
Sakai Y,Kaneko S,Sato Y,et al.Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with alpha-fetoprotein promoter and Cre/loxp system. Journal of Virological Methods . 2001Sakai Y, Kaneko S, Sato Y et al. Gene therapy for hepatocellular carcinoma using two ...
D.LoxP 免费查看参考答案及解析 题目: Or对cle中SYSTEM表空间是执行CRE对TE T对错LESP对CE命令建立的 免费查看参考答案及解析 题目: 使用cre对te d对t对错对se手工创建数据库的前提是要启动一个数据库实例到nomount状态。 免费查看参考答案及解析 题目: 华为时域增强小区间千扰协调包括两方面技术CRE( ...
Glucose intolerance in RIP-Cre mice could be explained, at least in part, by the observation that insulin secretion from isolated islets is impaired in these mice. It is also possible that Cre could cause recombination of pseudo loxP sites in β-cells and thereby compromise their function, ...
Cellular plasticity and dedifferentiation within the intestine can be explained, in part, by broadly permissive chromatin found in different stem cell, enterocyte, and secretory progenitor cell populations. In addition, more committed enteroendocrine and goblet cell lineages can undergo chromatin reorganizatio...
The Cre/loxP system is commonly used to knock out genes in specific cells and tissues at specific time points. Osx-GFP:Cre (Osx-Cre) mice have been used to target mineralized tissues, specifically bones and teeth, with the expression of the GFP/Cre fusion protein driven by the Osx ...