It is critically important to understand the vaccine effectiveness (VE) of COVID-19 vaccines among IC populations as recommendations are updated over time in response to the evolving COVID-19 pandemic. Areas covered A targeted literature review was conducted to identify real-world studies that ...
said, "We are glad that our study provides reassuring evidence on the COVID-19 vaccination effectiveness. I really believe that OMOP Common Data Model and federated analytics are the future of real-world evidence research. Extensive efforts are required at the harmonization phase but once the data...
Timely evaluation of the protective effects of Coronavirus Disease 2019 (COVID-19) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern is urgently needed to inform pandemic control planning. Based on 78 vaccine efficacy or effectiveness (VE) data from 4...
Figure2presents the aggregated data on vaccine effectiveness in preventing severe COVID-19 for different vaccines, variants and time since vaccination. These are key parameters of interest, as they have each been shown to independently influence neutralising antibody levels4,16,29, and hence may each...
Vaccine effectiveness of COVID-19 vaccines against B.1.1.529 (Omicron) variant Three case-control studies had evaluated the VE of COVID-19 vaccines against the Omicron variant [69,74,84]. Two mRNA vaccines (mRNA-1273 and BNT162b2) were included in this analysis. All three studies enrolled...
Unvaccinated people in B.C. are seven times more likely to contract COVID-19, 30 times more likely to end up in hospital and 50 times more likely to be lined up for a ventilator in intensive care, the latest data from the B.C. Centre for Disease Control show. ...
This case control study evaluates the estimated vaccine effectiveness associated with 2, 3, or 4 doses of COVID-19 mRNA vaccination for protection against
“after a discussion with the FDA.” Instead, they planned to conduct the analysis after 62 cases. But by the time the plan had been formalized, there had been 94 cases of Covid-19 in the study. It’s not known how many were in the vaccine arm, but it would...
Concerns about the common side effects of COVID-19 vaccines and their effectiveness are key to determining whether adults in Germany and the UK choose to get vaccinated against the virus, according to new research being presented at this year's ESCMID Gl
The Clalit Research Institute, in collaboration with researchers from Harvard University, analyzed one of the world's largest integrated health record databases to examine the effectiveness of the Pfizer/BioNTech BNT162B2 vaccine against the Delta varian