IVS2 ϩ3_ϩ6delAAGT is a 4 bp deletion beginning at the third base of intron 2 donor splice site (Table 3). It disrupts the highly conserved 5' splice site consensus sequence (30). Anal- ysis with a splice site prediction program (Splice Site Predic- tion by Neural Network, ...
RRM-containing proteins make use of sophisticated strategies to interact with a large repertoire of single-stranded sequences with a considerable range of affinities [16]. Both U2AF65 and PUF60 preferentially bind uridine (U)-rich RNA sequences at PPTs via their RRMs to recruit U2 small ...