GeneticRisk factorImagingCoronary heart diseaseScreeningCoronary heart disease (CHD) often presents suddenly with little warning. Traditional risk factors are inadequate to identify the asymptomatic high-risk individuals. Early identification of patients with subclinical coronary artery disease using noninvasive...
Personal and family history characteristics of genetic susceptibility to coronary artery disease. CAD, coronary artery disease; Close relative, first and/or second degree relative from one lineage; Established risk factors, elevated total and LDL cholesterol, low HDL cholesterol, hypertension, diabetes, ...
Moving forwards, genetic testing could enable precision medicine approaches by identifying subgroups of patients at increased risk of coronary artery disease or those with a specific driving pathophysiology in whom a therapeutic or preventive approach would be most useful....
Spontaneous coronary artery dissection (SCAD) is an important, female-predominant cause of myocardial infarction and sudden death.1Rather than arising secondary to atherosclerotic plaque rupture or intraluminal thrombus formation, SCAD occurs secondary to an intimal tear and/or the formation o...
elucidated underlying biology and informed the development of new therapeutics. Moving forwards, genetic testing could enable precision medicine approaches by identifying subgroups of patients at increased risk of coronary artery disease or those with a specific driving pathophysiology in whom a therapeutic ...
Moving forwards, genetic testing could enable precision medicine approaches by identifying subgroups of patients at increased risk of coronary artery disease or those with a specific driving pathophysiology in whom a therapeutic or preventive approach would be most useful. 展开 ...
Despite the notable recent scientific advances, our ability to detect and prevent premature coronary artery disease (CAD) remains limited, and the identification of patients at risk is yet to be based on objective scientific testing. Eliciting a family history of CAD currently remains the only avail...
"Further studies are necessary to examine factors associated with testing as well as testing completion to identify areas that may be more suitable for intervention to improve testing rates," the authors write. More information:Cheng-Wei Huang et al, Association Between Coronary Artery Disease Testin...
We performed a genome-wide association study in UK Biobank testing ∼9 million DNA sequence variants for association with coronary artery disease (4,831 cases and 115,455 controls) and carried out meta-analysis with previously published results. We identified 15 new loci, bringing the total ...
We performed a genome-wide association study in UK Biobank testing ∼9 million DNA sequence variants for association with coronary artery disease (4,831 cases and 115,455 controls) and carried out meta-analysis with previously published results. We identified 15 new loci, bringing the total ...