Cu chelation or ATP7A targeted therapy has not been exploited in CRC, but may be of particularly interest for cases where therapeutic resistance is imparted by oncogenic KRAS. Methods Cell culture, RNA interference, and viral infections IEC-6 and CRC cell lines (CACO-2, HCT116, DLD-1, SW...
Another issue is that the high electrical resistance of NaYF4, the near-infrared upconversion material employed in the PEC water-splitting system, creates a significant obstacle for the photo-carriers as they traverse the UC layer towards the conductive substrate. Consequently, this leads to a ...
These nanoparticles can exert their negative effect against the bacterial cell without puncturing it, thus reducing the possibilities of resistance development against NPs [26, 27]. Therefore, synthesizing NPs with antibacterial activity represents an attractive goal in the nanoscience field. Iron-based ...
The flank-carrying vector fragments (resulting from HindIII/AhdI digestions) were ligated to a HindIII enclosed gentamycin resistance cassette (from pBBR1MCS-5; [61]). The segment with the flanks and the gentamycin gene was cut with SphI and cloned into SphI-digested pRvS, yielding pAL2. ...
9 comparing changes in the volume resistance of tri-metal compared to bright nickel. The environments included exposure to a quick temperature change, salt spray, mixed gas, high temperature, damp heat and a sulfur-containing atmosphere. The data shows that tri-metal equals ...
Besides having excellent antimicrobial properties, metal oxide nanoparticles could be used for drug delivery and against multidrug resistance (MDR) pathogens. Metal nanostructures such as silver (Ag), gold (Au), and Iron (Fe) have been widely studied for their bioactivity and applications in various...
(90.1%) occurred at a high temperature (45 °C), which may be regarded as optimal for Cu2+biosorption. Increases in adsorbate affinity for the surface of adsorbent, increases in adsorbent pore size, and increases in driving force to overcome the mass transfer resistance of the adsorbate ...
FIG. 1 is a graph of pull force vs. storage time, illustrating the storage stability of copper bonding wires in comparison with coated copper bonding wires at 70° C. in air; FIG. 2 is a graph of pull force vs. PCT storage time, illustrating the corrosion resistance of the bonding wire...
Another property of ingot casting mold lubricants of great importance is thermal stability. This property is a measure of the resistance of the lubricant to vaporization or chemical degradation at high temperatures. Thermal degradation of lubricant to produce vapors in an ingot mold leads to several ...
The high density energy source for the method according to the present invention may be laser beams, TIG arc or electron beams. Laser beams are more widely usable than other high density energy sources when the electric resistance of the powder mixture or the base material is relatively high an...