FIELD: chemistry.;SUBSTANCE: method of converting alcohol containing an amide group into the corresponding carboxylic acid involves reaction of a primary amide alcohol of formula: R1-CONR2(CH2)mOH, where R1 is a linear or branched alkyl or alkenyl group, having 7-22 carbon atoms; R2 is H, ...
S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765) is an orally absorbed prodrug of (S)-3-({1-[(S)-1-((S)-2-{[1-(4-amino-3-chlorophenyl)...
Comparison of an Amide and Amine Salt as Friction Modifiers for a Magnetic Thin Film Medium© The frictional properties of a novel lubricant on a thin film magnetic medium are presented. The novel carboxylic amine salt has better frictional characte... H Kondo,A Seki,A Kita - 《A S L E...
Peptide and amide bonds may be formed by reacting 7 with a carboxylic acid halide or a mixed anhydride and a tertiary amine acid scavenger or alternatively by combining 7 and a carboxylic acid or protected amino acid with a wide variety of coupling reagents that are standard to the art of ...
-octahydro-1H-indole-2-carboxylic acid (1:1); (2S)-2-{[3-({4-[(4-methylphenyl)sulphonyl]-5-oxido-1,2,5-oxadiazol-3-yl}oxy)propionyl]amino}succinic acid—(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxy-carbonyl)-butyl]-amino}-propionyl]-octahydro-1H-indole-2-carboxylic acid (1...
Primary amide alcohol, it oxidizes this invention, to the amide carboxylic acid which corresponds it regards the method of being improved at high yield.ハリチアン,ビジヤンチエン,ハンローザ,ホセギレルモ
Synthesis and anticonvulsant properties of triazolo- and imidazopyridazinyl carboxamides and carboxylic acids Analogues of 3-amino-7-(2,6-dichlorobenzyl)-6-methyltriazolo[4,3-b]pyridazine PC25 containing amide or carboxylic acid function were synthesized and tested... Stéphane,Moreau,and,... - 《...
comprising at least one carboxylic function consisting of moisturizing the nitrile by amide functional group by reaction with water in the presence of a strong inorganic acid, and then to hydrolyze the ester functions in the carboxylic functions by reaction with water and a strong inorganic acid. ...
2-carboxylic acid 9 1-(S--alanyl)-1,2,3,4-tetra- 1-(-- N--[1-(ethoxycarbonyl)-3- hydroquinoline-2-carboxylate, phenylpropyl]alanyl)-1,2,3,4- -t-butyl ester tetrahydroquinoline-2-carboxylic acid ___ <- Previous Patent (Synergistine derivat...)|Next Patent (Pharmaceutical compo......
Disclosed are compounds, compositions and methods for inhibiting interleukin-1β (IL-β) protease activity. The compounds, N-(pyrimidinyl)-aspartic acid α-substituted methyl ketones and aspartic acid al