Common Mutation Triggers ALL RelapseKathy BoltzPhD
Firstly, using single-cell RNA sequencing (scRNA-seq), we analyzed paired samples of peripheral blood mononuclear cells (PBMCs) from five CVID patients at three distinct stages of the SARS-CoV-2 infection: (1) baseline, before viral infection, (2) progression, during infection, and (3) conv...
Landmark studies on plasma samples collected up to 120 days after surgery revealed ctDNA in 25% of patients, and a concerning 49% of those who experienced clinical relapses. To track subclonal architecture at low ctDNA levels non-invasively, we developed a bioinformatic tool called ECLIPSE. ...
Preparing for Common Relapse TriggersClinicians can establish tailored prevention strategies with clientsThere are a gazillion...By DuffyBrian
Preparing for Common Relapse Triggers; Clinicians Can Establish Tailored Prevention Strategies with ClientsThere are a gazillion reasons to drink (or drug). From tears of anguish to tears of joy, from...Duffy, Brian
HOTTIP was cited as the only lncRNA associated with the avoidance of immune surveillance by increasing IL6 expression in ovarian tumor cells, which triggers PD-L1 expression through the STAT3 pathway in neutrophils [109]. Therefore, targeting specific lncRNAs or modifying their activity to boost ...