The aim of this study is evaluation of Philadelphia chromosome in CML patients and JAK2 mutation in MPNs patients that had been referred to a hematology/oncology clinic in Kermanshah between 2010-2011.Material and methods: In this study we evaluated common genetic disorders in 124 MPNs patients....
Hematological traits are known to be heritable, and it has been suggested that genetic factors contribute significantly to the inter-individual variance of these traits. Here, we review our current knowledge regarding the genetic architecture of hematological traits in humans, most of which has been ...
Brainstem regions support vital bodily functions, yet their genetic architectures and involvement in common brain disorders remain understudied. Here, using imaging-genetics data from a discovery sample of 27,034 individuals, we identify 45 brainstem-associated genetic loci, including the first linked to...
Common genetic disorders such as neurofibromatosis type I (NF1), tuberous sclerosis, basal cell nevus syndrome (BCNS), incontinentia pigmenti, and X-linked... Jennifer,L,Hand - 《Current Opinion in Pediatrics》 被引量: 0发表: 2015年
No person is born with a choice of genes. Alterations in DNA can result from a mutation in a single gene, chromosome abnormalities, or multi-factorial disorders. When genetic disorders do occur, they are often rare, and affect one person among thousands of individuals. ...
In the general population, by contrast, about 1 in 88 people have either autism or Asperger's. 相比之下,普通人群只有约 1/88 的人患有自闭症或阿斯伯格综合征。 10 Other unusual parallels between prodigies and those with autism: they're both more likely to be male (though that finding may ...
As in adults, depression in children can be caused by any combination of things that relate to physical health, life events, family history, environment, genetic vulnerability, and biochemical disturbance. Depression is not a passing mood, nor is it a condition that will go away without proper ...
3 Other Common Canine Genetic Diseases 4 Should Genetic Disorders in Dogs discourage us? 5 Reference How are the majority of genetic diseases in dogs inherited? Genetic diseases can be inherited in various ways depending on the illness, and they can either bedominant orrecessive. ...
The structure of genetic and environmental risk factors for anxiety disorders in men and women. Arch Gen Psychiatry 2005; 62: 182–189. Article PubMed Google Scholar American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, 5th edn. American Psychiatric Publishing: : ...
By combining this genetic tool with metabolomics, we identify circulating α-hydroxybutyrate levels as a robust marker of an elevated hepatic cytosolic NADH/NAD+ ratio, also known as reductive stress. In humans, elevations in circulating α-hydroxybutyrate levels have previously been associated with ...