Genome, HumanGenetic Predisposition to DiseasePolymorphism, Single NucleotideThe article evaluates the genome-wide-association (GWA) studies of common diseases which aim to examine the variation in human genome. It states that GWA studies rely on linkage disequilibrium that enables single nucleotide ...
The genetics of common diseases: the implications of population variability In: Chadwick DJ, Cardew G, Eds. Variation in the Human Genome (Ciba Foundation Symposium 197). Chichester, UK: John Wiley and Sons 1996: pp. 300-11.Weatherall DJ. The genetics of common diseases: the implications of...
Ivanov: Genetics and Environment in Common Diseases Ivanov VI (1991) Some ethical aspects of genetic approaches to human health care: a developmental geneticist's point of view. In: Sram RJ, Bulyzhenkov V, Prilipko L, Christen (eds) Ethical issues of molecular genetics in psychiatry. Springer...
Advances in genetic mapping of human diseases have led to the identification of single locus susceptibility for several common disorders. There have been a number of reports of linkage for the psychiatric disorders manic-depressive illness and schizophrenia, but none of these linkage reports is unconte...
Age is a common risk factor in many diseases, but the molecular basis for this relationship is elusive. In this study we identified four disease clusters from 116 diseases in UK Biobank data, defined by their age-of-onset profiles, and found that diseases with the same onset profile are ge...
A new study published inNature Geneticson Sunday 16 September 2007 show that common, complex diseases are more likely to be due to genetic variation in regions that control activity of genes, rather than in the regions that specify the protein code. ...
Using haplotype blocks to map human complex trait loci. Understanding of linkage disequilibrium (LD) in human populations could facilitate the discovery of genes that influence complex human diseases. The 'HapMa... LR Cardon,Gonalo R. Abecasis - 《Trends in Genetics》 被引量: 688发表: 2003年...
et al. An atlas of genetic correlations across human diseases and traits. Nat. Genet. 47, 1236–1241 (2015). CAS PubMed PubMed Central Google Scholar Okbay, A. et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide...
The Rarest And Most Gruesome Genetic Diseases Known To Science What Happens When You Donate Your Body to Science Interesting Facts You Didn't Know About Yawning Doctors Reveal Warning Signs You Shouldn't Overlook Rare Genetic Features That You Probably Don't Have ...