A combination of two distinct in vitro amplification procedures for DNA typing of HLA-DRB and -DQB 1 alleles. Vox Sang. 1995;69:328–35.Fischer GF, Fae L, Petrasek M, Moser S. A combination of two distinct in vitro amplification procedures for DNA typ- ing of HLA-DRB and -DQB 1 ...
Human immunodeficiency virus type 1 (HIV-1)-specific broadly neutralizing monoclonal antibodies (bNAbs) have to date shown transient viral suppression when administered as monotherapy or as a cocktail of two antibodies1–4. A combination of three bNAbs p
The objective of the study was to examine the role of microsatellite instability (MSI) and BRAFV600Emutation in colorectal cancer (CRC) by categorising patients into more detailed subtypes based on tumour characteristics. Tumour samples from 762 populati
Annual yield loss in cacao is caused by a variety of pests and pathogens, the worst of which is black pod rot [10]. Black pod rot is caused by fourPhytophthoraspecies and accounts for 10 to 30% of pre-harvest yield loss [13,21]. The two most damaging members of this quartet areP. ...
Antigen-specific immunotherapy holds the potential to induce clinically effective anticancer T-cell responses and might be harnessed to guide and increase the specificity of cancer immunotherapy in future combination trials [3]. To this end, the exact knowledge of tumor-associated/specific T-cell epito...
The frequency of two polymorphisms in CYP2C8 gene in the population who failed is presented in Table 4. Out of the 10 patients in the CQ arm with parasite recurrence, one had the SNP G416A genotype indicative of reduced enzyme activity of CYP2C8. The AUC and half-life for chloroquine...
HLA-A*01, HLA-A*02, and HLA-B*07 are examples of different MHC class I alleles that can be expressed from these loci. TABLE 5 Expression frequencies F of HLA-A*02 and HLA-A*24 and the most frequent HLA-DR serotypes. Frequencies are deduced from haplotype frequencies Gf within ...
Two different statistics were used to compare the adequacy of the chosen tests in cases of small frequencies. When both tests yielded the same results, only results based on Fisher's exact test are reported. An identical approach was then applied for comparisons between PGS and CG. Based on ...
In Table 1, the first SNP on each chromosome is the lead SNP from the first round of GWAS analysis, the rest are the additional SNP(s) detected on a chromosome. Sixteen SNPs on chromosome 14 have the same P-value in the first round, and these SNPs are in high LD with the two ...
The procedure of the exact tree method is described below. First, we made cross-tabs of genotypes between the groups of stroke patients and healthy controls. Then, we com- pared the prevalence of these alleles between the groups and calculated the P value of Fischer's exact test (See ''...