Fusobacterium nucleatum (Fn), a bacterium present in the human oral cavity and rarely found in the lower gastrointestinal tract of healthy individuals1, is enriched in human colorectal cancer (CRC) tumours2–5. High intratumoural Fn loads are associated
ao estimate the reduction in colorectal cancer incidence and mortality due to CTC screening, the three CISNET models predicted colorectal cancer incidence and mortality rates when there is no screening and with CTC screening every 5 years starting at age 40, 50, or 65 years and ending at the ...
Article https://doi.org/10.1038/s41467-023-39374-9 Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex Received: 2 April 2022 Accepted: 9 June 2023 Check for updates Yilun Sun 1 , Simone A. Baechler1, Xiaohu ...
This agent may be potentially useful for treatment of inflammatory bowel diseases as well as their related colorectal cancer chemoprevention.Similar content being viewed by others Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1...
After 20-30 mins of local hyperthermia, I jump back in the bath and sip on a chilled fresh coconut. This is reported to have anti cancer properties (which is a bonus), but my main reason is that fresh coconut milk is a great way to replace the lost electrolytes. This becomes the hig...
Multimodal nanoparticles, utilizing quantum dots (QDs), mesoporous silica nanoparticles (MSNs), and gold nanoparticles (Au NPs), offer substantial potential as a smart and targeted drug delivery system for simultaneous cancer therapy and imaging. This method entails coating magnetic GZCIS/ZnS QDs with...
Recent evidence implicates microbial sulfidogenesis as a potential trigger of colorectal cancer (CRC), highlighting the need for comprehensive knowledge of sulfur metabolism within the human gut. Microbial sulfidogenesis produces genotoxic hydrogen sulfi
Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2013, Article ID 549705, 8 pages http://dx.doi.org/10.1155/2013/549705 Research Article Cytotoxic Activity of Kenaf Seed Oils from Supercritical Carbon Dioxide Fluid Extraction towards Human Col...
www.nature.com/scientificreports OPEN Curcumin mediates oxaliplatin- acquired resistance reversion in colorectal cancer cell lines through received: 23 December 2015 modulation of CXC-Chemokine/accepted:04April2016 NF-κB signalling pathwayPublished:19April2016 Vicenç Ruiz de Porras1,7, Sara ...
Cancer chemotherapy targeting frequent loss of heterozygosity events is an attractive concept, since tumor cells may lack enzymatic activities present in normal constitutional cells. To find exploitable targets, we map prevalent genetic polymorphisms to protein structures and identify 45 nsSNVs (non-synonym...