Dashwood, in Cancer Letters, 2006 Thus, in addition to its ability to act as a ‘blocking’ agent against early initiating events, recent evidence points to SFN as a ‘suppressing’ agent, helping to delay or reverse growth and/or survival of transformed cells (Fig. 2). The precise ...
Accumulating evidence demonstrated the significant role of cancer stem cells in cancer development [40, 41]. hTERT was found to be involved in the maintenance of stemness in cancer cells [42, 43]. The relationship between high expression of hTERT and inferior outcome in patients with melanoma wa...
000 pending casesfor herbicides causing cancer,and as a result, Vietnam likely thought it was finally time to seek justice for the victims of Agent Orange. Again, the biotech firm had supplied the US military with
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intravenously and in high doses (high-dose IVC). Early phase clinical trials have confirmed safety and indicated efficacy of IVC in eradicating tumour cells of various cancer types. In ...
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intravenously and in high doses (high-dose IVC). Early phase clinical trials have confirmed safety and indicated efficacy of IVC in eradicatin
colon carcinoma cells (Jordan et al., 2012). The effect of curcumin (CUR) in combination with etoposide (ETP) was evaluated in a nanoemulsion formulation against prostate cancer cells (PC3 and DU145). Moreover, their effects on cross talk between osteoblast and tumor cells leading to ...
Transthyretin amyloidoses encompass a variety of acquired and hereditary diseases triggered by systemic extracellular accumulation of toxic transthyretin aggregates and fibrils, particularly in the peripheral nervous system. Since transthyretin amyloidos
First, to determine if breast cancer exosomes can be readily transferred to endothelial cells we cultured the endothelial cell line EA.hy926 on matrigel in the presence of purified exosomes isolated from MCF7 cells that were pre-labeled with the nucleic acid binding dye, acridine orange (AO). ...
Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy. Clin Cancer Res 2013; 19: 2995–3007. Cell Death and Disease ML-9 targets autophagy and cell death A Kondratskyi et al 12 13. White E. Deconvoluting the context-dependent role for autophagy in cancer....
R. officinalisL aqueous extract was evaluated on adherent cells in microplates after exposure for 24, 48 and 72 h. The analyses were performed by (i) MTT test; (ii) NR assay; (iii) apoptosis with ethidium bromide/acridine orange (EB/AO), evaluated by fluorescence microscopy, which analyz...