Although clinic experiments and gene profiling analyses had been well performed, to our knowledge, systemic coexpression analysis of human genes for this cancer is still limited to date. Here, using the published data GSE75037, we built the coexpression modules of genes by Weighted Gene Co-...
方法/步骤 1 根据基因在样本中的信号表达值,利用基因间的相互作用(相关系数)来拟合基因的无标度网络关系,构建基因间的共表达网络,结果样式如图。点:图中每个圆点代表一个基因。2 颜色:对于两分组(例如实验组和对照组),红色点为上调基因,蓝色为下调基因,对于多分组(例如 组1,组2,组3),由于差异基...
Three coexpression gene modules displaying significant expression association in a jaw-specific manner were selected for further investigations of their potential regulatory networks (Fig.4a). The Cyan and Plum2 modules showed positive correlation and Blue module had negative correlation. The largest modul...
PCR扩增西门利克森林病毒(SFV)亚基因组启动子26S序列及人工合成Linker,将其插入基于SFV复制子的“自杀性”DNA疫苗表达载体pSCA1的多克隆位点,获得含2个26S启动子并能同时驱动双基因共表达的“自杀性”DNA疫苗表达载体pSCA2。 更多例句>> 6) gene coexpres-sion network 基因共表达网络补充...
Its molecular basis is not entirely clear, although profound gene expression changes have been reported, and there are some known and other presumed overlaps with normal aging process. Identification of genes with aging - or HGPS-associated expression changes is thus an important problem. However, ...
functional protein expression and biosynthesis of specialized products in plants. Multi-omics analysis has become a powerful approach to identify gene-to-metabolite correlations26. The integration of modern omics technologies provides a great opportunity for better understanding plant defense mechanisms agains...
Weirauch MT. Gene coexpression networks for the analysis of DNA micro- array data. Applied statistics for network biology: methods in systems biology. 2011;. doi:10.1002/9783527638079.ch11.Weirauch MT (2011) Gene coexpression networks for the analysis of DNA microarray data. In: Dehmer M, ...
Gene expression of Hspb3 n Mocs2, which codes heat shock protein and, molybdenum cofactor synthesis, respectively, in substantia nigra is reduced in cataleptic CBA and D13 mice compared to catalepsy-resistant AKR mice. These genes can be considered as the most likely genes candidate of catale...
In Arabidopsis, a large number of genes involved in the accumulation of seed storage reserves during seed development have been characterized, but the relationship of gene expression and regulation underlying this physiological process remains poorly understood. A more holistic view of this molecular inte...
Gene coexpression analyses are a powerful method to predict the function of genes and/or to identify genes that are functionally related to query genes. The basic idea of gene coexpression analyses is that genes with similar functions should have similar expression patterns under many different cond...