Codon usage bias (CUB) is the nonrandom usage of synonymous codons in which some codons are more preferred to others.CUB can be determined by mutation pressure and selection. Various approaches have been used to understand the pattern of CUB in the mitochondrial ND (MT-ND or ND) genes ...
Although codon usage bias in the viral genome is a common phenomenon and a factor worth considering in the design of viral vaccines, there are currently very limited reports on the VEEV genome CUB, and this strategy has yet to be employed in the development of VEEV vaccines. Our recent ...
<italic>Chaetomium thermophilum</italic> has strong lignocellulose degradation ability, having broad application prospects to be developed as an excellent host for recombinant protein expression. The codon bias of the protein expression h
Codon usage bias (CUB) is an important evolutionary feature in a genome and has been widely documented from prokaryotes to eukaryotes. However, the significance of CUB in the Asteraceae family has not been well understood, with no Asteraceae species having been analyzed for this characteristic. ...
Codon usage biasChloroplast genomeMesona chinensisBenthEvolution and cluster analysisMesona chinensis Benth (MCB) is one of the main economic crops in tropical and subtropical areas. To understand the codon usage bias (CUB) in M. chinensis Benth, chloroplast genome is essential to study its genetic...
Eighteen of the 20 amino acids are each encoded by more than one synonymous codon. Due to differential transfer RNA supply within the cell, synonymous codons are not used with equal frequency, a phenomenon termed codon usage bias (CUB). Previous studi
Codon usage bias (CUB) refers to the phenomenon where synonymous codons are not used with equal frequencies during translation of genes. CUB is a common phenomenon in a wide variety of organisms, including prokaryotes and eukaryotes [1]–[3]. Many factors have been reported to influence codon ...
README cubfits is an R package providing fits of codon usage bias. For installing cubfits, - see "INSTALL" for detais. About Codon Usage Bias Fits Resources Readme License MPL-2.0 license Citation Cite this repository Activity Stars 5 stars Watchers 3 watching Forks 6 forks ...
(see Supplementary Table S1 for the RSCU of human cells) Even without identifying the exact molecular process, it is known that the synonym codon usage bias (CUB) is common in many species12. Just as the model organisms and systems for CUB analysis, the tumor environment can be seen as a...
The different algorithms and tools used in designing synthetic genes need to consider the recipient strain's codon usage bias (CUB), GC-content and changes in protein secondary structures that may be introduced (Lanza et al., 2014; Villada et al., 2017). Initial optimization strategies used ...