Hu C, Chen J, Ye L, Chen R, Zhang L, Xue X (2014). Codon usage bias in human cytomegalovirus and its biological implication. Gene 545(1):5-14.Hu C, Chen J, Ye L, Chen R, Zhang L, Xue X. Codon usage bias in human cytomegalovirus and its biological implication . Gene . 2014...
Codon usage bias, the frequency of occurrence of synonymous codons in coding DNA, in human cells is limited by amino acids needed for protein structure/function and by genome signatures (dinucleotide relative abundances). In contrast, translational and transcriptional influences appear to play a minor...
In the class I loci, the same level of moderate codon bias is seen for HLA-B, HLA-C, Patr-A, Patr-B, and Patr-C, while at HLA-A the level of codon bias is lower. There is a correlation between codon usage bias and G+C content in the A and B loci in humans and chimps, ...
Human housekeeping genes are compact Trends in Genetics Journal2003, Trends in Genetics Eli Eisenberg, Erez Y. Levanon It has been noted that codon usage bias in non-mammalian organisms is correlated with the expression level and with the gene length [17–19]. These results led to the conject...
C. The extent of codon usage bias in human RNA viruses and its evolutionary origin. Virus Res. 92, 1–7 (2003). Article CAS PubMed Google Scholar Cherry, J. M. et al. Saccharomyces genome database: the genomics resource of budding yeast. Nucleic Acids Res. 40, D700–D705 (2012)....
In numerous species, from bacteria to Drosophila, evidence suggests that selection acts even on synonymous codon usage: codon bias is greater in more abundantly expressed genes, the rate of synonymous evolution is lower in genes with greater codon bias, and there is consistency between genes in th...
(see Supplementary Table S1 for the RSCU of human cells) Even without identifying the exact molecular process, it is known that the synonym codon usage bias (CUB) is common in many species12. Just as the model organisms and systems for CUB analysis, the tumor environment can be seen as a...
Codon usage of a virus must coevolve with its host for efficient viral replication, therefore, we conduct a comprehensive analysis of codon usage bias in human-isolated AIVs to test their adaptation to host expression system. The relative synonymous codon usage (RSCU) pattern, and the codon ...
ORFSCANNINGtakes codon usage into account to facilitate the location of genes, since realEXONSare likely to display a bias for certain codons, whereas runs of chance triplets will not. Codon usage is also called codon bias. Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. ...
In subject area: Immunology and Microbiology Codon usage bias refers to the differences in the frequency of usage for a certain base triplet for a given amino acid among organisms. From: Journal of Allergy and Clinical Immunology, 2008