Coding versus non-coding: translatability of short ORFs found in putative non-coding transcripts. Biochimie 93, 1981–1986 (2011). Article CAS PubMed Google Scholar Kapranov, P. et al. The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated ...
Mutations: Driver Versus Passenger Noncoding Driver Mutations In addition to coding driver mutations, recent efforts directed at the noncoding regions of the genome have revealed the presence of noncoding driver mutations. Major efforts to characterize the functional properties of noncoding DNA, particul...
Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose non-synonymous transcription to breast cancer related mRNAsReiche, KristinKasack, KatharinaSchreiber, StephanTorben, LDue, Eldri U
a WGCNA-GSEA analysis of mito versus non-mito-SEPs in human failing heart reveals strong anti-correlation of mito-SEPs with inflammation. Each row represents one pathway and the pathways are separated into those that are involved in metabolism and those that are involved in inflammation. Color ...
The coordination of chromatin remodeling is essential for DNA accessibility and gene expression control. The highly conserved and ubiquitously expressed SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex plays a central role in cell ty
Regulation of imprinting in clusters: Noncoding RNAs versus insulators. Adv Genet. 2008; 61 :207–223.Wan LB, Bartolomei MS. Regulation of imprinting in clusters: noncoding RNAs versus insulators. Adv Genet. 2008; 61 :207–223.Wan L.B., Bartolomei M.S. Regulation of imprinting in clusters...
b Venn diagram analysis for differential expression genes from sequencing and microarray during additional molar morphogenesis showing more changes in gene expression at E60 versus E50 and relatively fewer changes between E70 and E60. c Pathway enrichment from microarray and sequencing between two stages ...
throughplantnoncodingtranscription. Thecodingversusthenoncodinggenome Longbeforetheeraofnext-generationsequencingtechnol- ogies,thepoorcorrelationbetweenDNAamountand organismcomplexity,theso-called‘C-valueparadox’[1], hadalreadydrawntheattentionofthescientificcommu- ...
& Mayr, M. Noncoding RNAs versus protein biomarkers in cardiovascular disease. Trends Mol. Med. 26, 583–596 (2020). CAS PubMed Google Scholar de Gonzalo-Calvo, D. et al. Circulating non-coding RNAs in biomarker-guided cardiovascular therapy: a novel tool for personalized medicine. Eur. ...
More than 98% of the human genome is made up of non-coding DNA, but techniques to ascertain its contribution to human disease have lagged far behind our understanding of protein coding variations. Autism spectrum disorder (ASD) has been mostly associated