Co-selection of antibiotic and metal resistance, ArtículoThere is growing concern that metal contamination functions as a selective agent in the proliferation of antibiotic resistance. Documented associations between the types and levels of metal contamination and specific patterns of antibiotic resistance ...
Co-selection of antibiotic resistance via copper shock loading on bacteria from a drinking water bio-filter
antibiotic-resistance genes in both natural and clinical settings. In addition to metals, other toxicants are implicated in the co-selection of antibiotic resistance, including quaternary ammonium compounds and anti- fouling agents and detergents [6,7]. However, in this ...
Heavy metals select for metal resistance but can also co-select for resistance to antibiotics, which is a global health concern. We here document metal concentration, metal resistance and antibiotic resistance along a sediment archive from a pond in the North West of the United Kingdom covering ...
Antimicrobial metal ion resistance and its impact on co-selection of antibiotic resistance There is a growing body of evidence that biocide and antimicrobial metal use may be contributing to the antibiotic resistance problem. Jon Hobman, Associate...
Because of the genetic link between acquired copper (tcrB) and antibiotic resistance in Enterococcus spp., we hypothesized that copper supplementation may exert selection pressure for enterococci to become resistant to macrolides and tetracyclines, and possibly to other antibiotics. We conducted studies ...
Antibacterial biocides and metals can co-select for antibiotic resistance when bacteria harbour resistance or tolerance genes towards both types of compounds. Despite numerous case studies, systematic and quantitative data on co-occurrence of such genes on plasmids and chromosomes is lacking, as is know...
Bacterial pathogens resistant to multiple antibiotics are emergent threat to the public health which may evolve in the environment due to the co-selection of antibiotic resistance, driven by poly aromatic hydrocarbons (PAHs) and/or heavy metal contaminations. The co-selection of antibiotic resistance ...
Finally, we identify strong negative epistasis between two unrelated resistance mechanisms: thetetracycline resistance gene and loss-of-functionmutations involved in aminoglycoside tolerance. Our study highlights important constraints that may allow better prediction and control of antibiotic resistance evolution...
If resistance genes for both antibiotics and biocides/metals are physically located on the same plasmid, metal/biocide exposure can also promote horizontal gene transfer (HGT) of antibiotic resistance. Today, conjugative plasmids carrying ARGs have become a major health challenge in clinical settings [...