Antibiotic resistance genesMobile genetic elementsCo-selectionMetal toxicityqPCR chipUrban soilsAntibiotic resistance genes (ARGs) constitute emerging environmental pollutants and pose risks to public health. Toxic metals are known to select for metal-resistant bacteria in metal-contaminated soils, but there...
The link between metal ion resistance and antibiotic resistance, and how increasing the use of non-antibiotic antimicrobials may drive co-selection
and can subsequently represent a long-term selection pressure [5]. Thus, there are concerns regarding the potential of metal contamination to maintain a pool of antibiotic-resistance genes in both natural and clinical settings. In addition to metals, other toxicants are ...
Taking a temporal, rather than a spatial or experimental approach has the advantage that the distinct timescales of historical metal- and antibiotic pollution can be separated, allowing the untangling of selection and co-selection for resistance. Concentrations of heavy metals and other pollutants have...
The high frequency of antibiotic resistance is a global public health concern. More seriously, widespread metal pressure in the environment may facilitate the proliferation of antibiotic resistance via coselection of antibiotic resistance genes (ARGs) and metal resistance genes (MRGs). Given the lack ...
Co-selection of antibiotic resistance genes, and mobile genetic elements in the presence of heavy metals in poultry farm environments. Sci Total Environ. 2021;755:142702. Article CAS PubMed Google Scholar Qin J, Li Y, Cai Z, Li S, Zhu J, Zhang F, Liang S, Zhang W, Guan Y, Shen ...
The plasmid also carries tetracycline [tet(M)] and macrolide [erm(B)] resistance genes. Because of the genetic link between acquired copper (tcrB) and antibiotic resistance in Enterococcus spp., we hypothesized that copper supplementation may exert selection pressure for enterococci to become ...
Short-term copper exposure as a selection pressure for antibiotic resistance and metal resistance in an agricultural soil Owing to the similar mechanisms of antibiotic and metal resistance, there is a growing concern that metal contamination may select for antibiotic resistanc... K Wei,YJ Zhang,X ...
During the years of medical and veterinary usage of antibiotics, some of the drugs have been constantly escaping into the environment, creating an additional selection pressure for resistance [4]. As expected, AR bacteria can be found in both pristine and anthropogenically influenced environments at ...
A variety of biocides and metals, at concentrations found in different natural and polluted environments, have the ability to co-select for antibiotic-resistant bacteria and resistance plasmids [12]. Thus, it is possible that opportunities for co-selection are widespread across environments, taxonomic...