Centaur and Intel clearly have different goals. Haswell-E serves as a high end desktop chip, where it runs well above 3 GHz to achieve higher CPU performance. That higher performance especially applies in applications that don’t have lots of parallelism. To make that happen, Intel dedicates ...
Worse, TSMC’s 7nm process lets AMD pack 64 of those cores into one socket. In my view, CNS has to be ported to a 7nm class process to have any chance after 2020. It’s hard to guess what that would look like, but I suspect a CNS successor on 7nm would fill a nice niche. It...
Hydrocephalus (increased ventricular size due to CSF accumulation) is a common finding in human ciliopathies and in mouse models with genetic depletion of the multiciliated cell (MCC) cilia machinery. However, the contribution of MCC to CSF dynamics and,
Full size image Finally, supplementary sub-analyses on inter-rater manual segmentation (ICC between all raters = 0.73) and inter-scan machine learning segmentation performance (ICC between consecutive segmentations = 0.99) are summarized in the Supplementary Materials. We also investigated the...
We found both AAV-PHP.B and AAV-PHP.eB resulted in marked disruption of the NeuN gene by CRISPR/Cas9, significantly greater than AAV9 in several brain regions and spinal cord. In contrast, only modest disruption of the GFAP gene and the MOG gene was observed by all three AAV variants. ...
In multicellular organisms epithelial and endothelial cells form selective permeable interfaces between tissue compartments of different chemical compositions. Tight junctions which connect adjacent cells, control the passage of molecules across the barrier and, in addition, facilitate active transport processes...
A new form of long-term depression in the perirhinal cortex. Nature Neurosci. 3, 150–156 (2000). Article CAS PubMed Google Scholar Laezza, F., Doherty, J. J. & Dingledine, R. Long-term depression in hippocampal interneurons: joint requirement for pre- and postsynaptic events. Science...
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Engineering Aerospace Automotive eBook Packages eBook Package english full Collection eBook Package english Engineering Authors Wei Quan (5) Xiaolin Gong (5) Jiancheng Fang (5) Jianli Li (5) Author Affiliations 5. Beijing University of Aeronautics and Astronautics, Beijing, China Continue...
Full size image Verification of the transwell barrier model setup and putative cargo receptor expression To study the transport of the selected cargo antibodies, we used a Transwell setup with cells seeded on the top chamber filter insert to form a barrier towards the bottom chamber, enabling analy...