depression Doctor's response A depressant, by definition, reduces or diminishes a function or activity. A CNS depressant, therefore, would depress the activity of the central nervous system (CNS). Somedrugsthat are commonly used assedatives,hypnotics(sleep aids), and anesthetics are CNS depressants...
CNS depression in an infant after the ingestion of tobacco: a case report. Vet Hum Toxicol. 1988;30:20 -22Borys DJ, Setzer SC, Ling LJ. CNS depression in an infant after the ingestion of tobacco: a case report. Veterinary and Human Toxicology 30: 20–22, 1988...
2018年2月15日,胡海岚团队在Nature期刊同期发表两篇研究论文【2、3】。 第一篇题为:Ketamine blocks bursting in the lateral habenula to rapidly relieve depression,该研究首次揭示了外侧缰核(LHb)的一种特殊放电方式簇状放电,是抑郁症发生的充分条件,而氯胺酮通过有效阻止该脑区的簇状放电产生快速抗抑郁的疗效,该...
第一篇题为:Ketamine blocks bursting in the lateral habenula to rapidly relieve depression,该研究首次揭示了外侧缰核(LHb)的一种特殊放电方式簇状放电,是抑郁症发生的充分条件,而氯胺酮通过有效阻止该脑区的簇状放电产生快速抗抑郁的疗效,该研究还揭示了T型钙通道(T-VSCC)可作为新型抗抑郁靶点。 第二篇论文题...
提到中枢类疾病,其实每个人都能说上几个,最为人所知的有老年痴呆症(又叫阿尔茨海默症(Alzheimer's disease,AD))、帕金森症(Parkinson's disease,PD)、抑郁(Depression)、精神分裂症(Schizophrenia)、癫痫(Epilepsy)、中风(又叫脑卒中,Stroke),...
Tetryzoline overdose: CNS depression and hypothermia in paediatric patients: 3 case reports
Allopregnanolone-based treatments forpostpartum depression: Why/how do they work? Neurobiology of Stress2019, 11, 100198. SamanthaMeltzer-Brody, etc. Brexanolone injection in post-partum depression:two multicentre, double-blind, randomised, placebo-controlled, phase3 trials [J]. Lancet, 2018,...
Long-term depression (LTD) in the CNS has been the subject of intense investigation as a process that may be involved in learning and memory and in various pathological conditions. Several mechanistically distinct forms of this type of synaptic plasticity have been identified and their molecular mec...
最为人所知的中枢类疾病包括老年痴呆症(又叫阿尔茨海默症Alzheimer's disease,AD)、帕金森症(Parkinson's disease,PD)、抑郁(Depression)、精神分裂症(Schizophrenia)、癫痫 (Epilepsy)、中风(又叫脑卒中,Stroke),还有在肿瘤领域经常能听到的原发性脑瘤和脑转移(Brain metastasis)等。从更精确的分类上来说,约翰...
2018年2月15日,浙江大学胡海岚课题组在Nature发表了2篇背靠背地研究论文,题目分别为“Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression”及“Ketamine blocks bursting in the lateral habenula to rapidly relieve depression”, ...