depression Doctor's response A depressant, by definition, reduces or diminishes a function or activity. A CNS depressant, therefore, would depress the activity of the central nervous system (CNS). Somedrugsthat are commonly used assedatives,hypnotics(sleep aids), and anesthetics are CNS depressants...
第一篇题为:Ketamine blocks bursting in the lateral habenula to rapidly relieve depression,该研究首次揭示了外侧缰核(LHb)的一种特殊放电方式簇状放电,是抑郁症发生的充分条件,而氯胺酮通过有效阻止该脑区的簇状放电产生快速抗抑郁的疗效,该研究还...
Carisoprodol overdose: CNS depression: case report
1.https://news.bms.com/news/corporate-financial/2023/Bristol-Myers-Squibb-Strengthens-Neuroscience-Portfolio-with-Acquisition-of-Karuna-Therapeutics/default.aspx.2.Merck ends PhII trials of Alzheimer’s and depression small molecule after liver toxicity observations – Endpoints News (endpts.com).3.St...
提到中枢类疾病,其实每个人都能说上几个,最为人所知的有老年痴呆症(又叫阿尔茨海默症(Alzheimer's disease,AD))、帕金森症(Parkinson's disease,PD)、抑郁(Depression)、精神分裂症(Schizophrenia)、癫痫(Epilepsy)、中风(又叫脑卒中,Stroke),...
2. Yang Y#, Cui Y#, Sang K#, Dong Y#, Ni Z, Ma S, Hu H. Ketamine blocks bursting in the lateral habenula to rapidly relieve depression.Nature.554: 317-22. (2018) (# co-first)(Research article, featured byNature,Nature Review Neuroscience,NeuronandFaculty 1000) ...
Allopregnanolone-based treatments forpostpartum depression: Why/how do they work? Neurobiology of Stress2019, 11, 100198. SamanthaMeltzer-Brody, etc. Brexanolone injection in post-partum depression:two multicentre, double-blind, randomised, placebo-controlled, phase3 trials [J]. Lancet, 2018,...
therapies, the latter being particularly indicated when the depression has been precipitated by stressful and depressing events or situations. Psychosocial and environmental interventions are important in all types of depression and may prove more effective than the use of antidepressants for milder ...
最为人所知的中枢类疾病包括老年痴呆症(又叫阿尔茨海默症Alzheimer's disease,AD)、帕金森症(Parkinson's disease,PD)、抑郁(Depression)、精神分裂症(Schizophrenia)、癫痫(Epilepsy)、中风(又叫脑卒中,Stroke),还有在肿瘤领域经常能听到的原发性脑瘤和脑转移(Brain metastasis)等。从更精确的分类上来说,约翰霍普金斯...
2022年6月,北京中医药大学东方医院郭蓉娟教授课题组在国际知名学术期刊CNS Neuroscience & Therapeutics(中枢神经系统神经科学与治疗, IF=7.035)在线发表了题为“Shugan granule contributes to the improvement of depression-like behaviors in chronic restraint stress-stimulated rats by altering gut microbiota(舒肝颗粒...