第一篇题为:Ketamine blocks bursting in the lateral habenula to rapidly relieve depression,该研究首次揭示了外侧缰核(LHb)的一种特殊放电方式簇状放电,是抑郁症发生的充分条件,而氯胺酮通过有效阻止该脑区的簇状放电产生快速抗抑郁的疗效,该研究还...
Carisoprodol overdose: CNS depression: case report
提到中枢类疾病,其实每个人都能说上几个,最为人所知的有老年痴呆症(又叫阿尔茨海默症(Alzheimer's disease,AD))、帕金森症(Parkinson's disease,PD)、抑郁(Depression)、精神分裂症(Schizophrenia)、癫痫(Epilepsy)、中风(又叫脑卒中,Stroke),...
Walton, N.; Maguire, J. Allopregnanolone-based treatments forpostpartum depression: Why/how do they work? Neurobiology of Stress2019, 11, 100198. SamanthaMeltzer-Brody, etc. Brexanolone injection in post-partum depression:two multicentre, double-blind, randomised, placebo-controlled, phase3 tri...
2.Merck ends PhII trials of Alzheimer’s and depression small molecule after liver toxicity observations – Endpoints News (endpts.com).3.Study Details | Efficacy and Safety of MK-1942 as an Adjunct Therapy in Participants With Mild to Moderate Alzheimer's Disease Dementia (MK-1942-008) | ...
2. Yang Y#, Cui Y#, Sang K#, Dong Y#, Ni Z, Ma S, Hu H. Ketamine blocks bursting in the lateral habenula to rapidly relieve depression.Nature.554: 317-22. (2018) (# co-first)(Research article, featured byNature,Nature Review Neuroscience,NeuronandFaculty 1000) ...
Chlorpromazine caused CNS depression, hypotension and miosis; EPS and cardiac effects were rare, and the toxic dose was estimated to be 15 mg/kg. ... GK Isbister,CR Balit,HA Kilham - 《Drug Safety》 被引量: 47发表: 2005年 Severe cardiovascular side effects of olanzapine in an elderly pat...
最为人所知的中枢类疾病包括老年痴呆症(又叫阿尔茨海默症Alzheimer's disease,AD)、帕金森症(Parkinson's disease,PD)、抑郁(Depression)、精神分裂症(Schizophrenia)、癫痫(Epilepsy)、中风(又叫脑卒中,Stroke),还有在肿瘤领域经常能听到的原发性脑瘤和脑转移(Brain metastasis)等。从更精确的分类上来说,约翰霍普金斯...
Ethanol‐Induced CNS depression and divided attention Subject performed a divided attention task in which they detected occurrences of a target letter in a stimulus figure which was a large letter made up of a... SA Millar,L Duncan,B Tiplady - 《Human Psychopharmacology Clinical & Experimental》...
论文标题:Accelerated photochemical reactions at oil-water interface exploiting melting point depression 期刊:Science ( IF 56.9 ) 发表时间:2024/2/15 惟小研导读: 这项研究发现了在水介质中形成的芳香烃、杂环化合物、烯胺或酯类配对聚集体,通过降低基质熔点引入了油水相界面,从而加速光化学反应。反应物中的活性...