The nucleotide sequence of the genes encoding this novel beta-lactamase was found to be >94% identical to the nucleotide sequences of the plasmid-mediated AmpC-type beta-lactamases originating from Citrobacter freundii. This enzyme differed from CMY-2 by 3 amino acid substitutions and was ...
CMY-2 is the most commonly acquired ampicillin C (AmpC)-type [beta]-lactamase found in E. coli that cause human infections (3). The aim of this study was to investigate whether cephalosporin-resistant E. coli are present in retail raw meat and ready-to-eat meat products in our area 5...
Ceftriaxone resistance was due to the production of the CMY-2 AmpC beta-lactamase by seven isolates and the CTX-M-14 beta-lactamase by the remaining isolate. Both beta-lactamase genes were carried on conjugative plasmids. In a 2.5-kb region encompassing the bla(CMY-2) gene, at nucleotide ...
1996_A Bauernfeind_Characterization of the plasmidic beta-lactamase CMY-2, which is responsible for cephamycin resistance A NTIMICROBIAL A GENTS AND C HEMOTHERAPY , Jan. 1996, p. 221–224 Vol. 40, No. 10066-4804/96/$04.0010Copyright q 1996, American Society for MicrobiologyCharacterization of...
Thus in this study, we aimed to characterize extended-spectrum-beta-lactamase (ESBL) and acquired-AmpC-beta-lactamase (aAmpC)-producing Escherichia coli isolates from chicken faeces and raw meat in Tunisia. During the year 2018, 286 faecal chicken swabs and 47 raw chicken meat samples were ...
AmpC BER is an extended substrate spectrum class C β-lactamase with a two-amino-acid insertion in the R2 loop compared with AmpC EC2. The crystal structures of AmpC BER (S64A mutant) and AmpC EC2 were determined. Structural comparison of the two proteins revealed that the insertion increa...
Dissemination of IncF plasmids carrying beta-lactamase genes in Gram-negative bacteria from Nigerian hospitals. J Infect Dev Ctries. 2013;7(5):382–90. doi:10.3855/jidc.2613. Article CAS PubMed Google Scholar Doumith M, Dhanji H, Ellington MJ, Hawkey P, Woodford N. Characterization of ...
Cross resistance to cefiderocol and ceftazidime-avibactam in KPC beta-lactamase mutants and inoculum effect Objectives: Ceftazidime-avibactam and cefiderocol are recently commercialized molecules active against highly drug-resistant bacteria, including carbapenem... CA Hobson,A Cointe,H Jacquier,... - ...
beta-lactamase CMY-2 beta-lactamase CMY-2(beta-lactamase CMY-2) CAS: 化学式: 中文名beta-lactamase CMY-2 英文名beta-lactamase CMY-2 英文别名beta-lactamase CMY-2
coli . The ESBL/pAmpC type beta-lactamases were as follows: CMY-2 ( n =46), CMY-2+TEM-1b ( n =63), SHV-12 ( n =5), SHV-12+TEM-1b ( n =12), CTX-M-3 ( n =14), CTX-M-3+TEM-1b (n=1), CTX-M-15 ( n =4), CTX-M-15+TEM-1b (n=4), and CTX-M-1 (...