例句:AmpC beta-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae and a few other organisms, where they mediate resistance to cephalothin, cefazolin, cefoxitin, most penicillins, and beta-la...
Enterobacteriaceae is one of the most important causes of critical nosocomial and community-onset bacterial infections. In recent decades, the spread of resistance to 尾-lactam antibiotics has increased among the Enterobacteriaceae due to the different mechanisms such as AmpC beta-lactamase. This study...
Early-onset neonatal meningitis caused by an AmpC beta-lactamase-producing Escherichia coli is described for the first time; the plasmid was identified as a transferable CMY-2 family beta-lactamase. Limited experience with newer antibiotics and pharmacokin...
Most strains of P aeruginosa (as well as Enterobacter spp, Citrobacter freundii, Providencia spp, Morganella morganii, and Serratia spp) that are resistant to third-generation cephalosporins produce a functional group 1 (molecular class C) beta-lactamase. A representative of this class is the Amp...
Background objective: AmpC β-lactamases are clinically significant because they may confer resistance to a wide variety of β-lactam drugs, including α-methoxy-β-lactams, such as cefoxitin, narrow-, expanded- and broad-spectrum cephalosporins, β-lactam-β-lactamase inhibitor combinations and ...
阴沟肠杆菌去阻遏持续高产AmpC酶和超广谱β-内酰胺酶(ESBLs)的检测 Coudron PE, Moland ES,Thomson KS. Occurrence and detection of AmpC β-lactamase among Escherichia coli, and Proteus mirabillis isolates at a Veteran' s Medical Center[ J]. J Clin Microbiol, 2000, 38 : 1791. Fortineau N, ...
AmpC beta-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae and a few other organisms, where they mediate resistance to cephalothin, cefazolin, cefoxitin, most penicillins, and beta-lactamase inhibitor-beta-lactam combinations. In many bac...
The expression of chromosomal AmpC beta-lactamase in Pseudomonas aeruginosa is negatively regulated by the activity of an amidase, AmpD. In the present stu... N Bagge,O Ciofu,M Hentzer,... - 《Antimicrobial Agents & Chemotherapy》 被引量: 509发表: 2002年 Structure of the extended-spectrum ...
Background: Beta-lactam resistance in Gram-negative bacteria, especially Escherichia coli, is a main clinical problem. It is often caused by the co-production of 尾-lactamases, particularly extended-spectrum 尾-lactamases (ESBLs) and AmpC enzymes. It may lead to a problem for diagnosis via ...
The first beta-lactamase enzyme was identified against penicillin and after that various beta-lactamases have emerged due to intensive use of antibiotics, and, therefore, they need to be classified.1 Beta-lactamases are also divided into four groups according to their biochemical properties and subs...