This article discusses the interpretation of cytomegalovirus (CMV) serology in a pregnant patient. The patient had an increase in CMV IgG levels and a decrease in Rubella IgG levels during her pregnancy. Avidity testing indicated a high likelihood of a previous CMV infection. Amniocentesis...
Widespread use of these assays will allow for comparison of results between centers and meaningful interpretation of the significance of viral load measurements.Methods. Sequential samples from 52 patients after renal transplantation were tested in the murex hybrid capture assay (HCA) and the Roche ...
CMV, IgM CMV, IgG Possible Interpretation Negative Negative No current or prior infection; no immunity (person is susceptible to primary infection) Symptoms due to another cause OR immune system cannot produce adequate amount of antibody (immunocompromised) Positive Negative Recent active primary infectio...
The results were back-transformed for easier interpretation. Relative frequencies were compared using Fisher's exact test. CYTOMEGALOVIRUS INACTIVATION IN MILK 531 Figure 1. Virological parameters of different procedures for CMV inactivation in breast milk. (A) Stability of viral DNA after freezing or ...
EB viral load measurement was also performed as part of the clinical evaluation for symptomatic illness. EB viral loads were performed at a central lab by one of the investigators (DR) using previously published methods (12), and reported as genome copies per 105 peripheral blood lymphocytes (...
Founding bodies had no role in the design of the study and collection, analysis, and interpretation of data and in writing of the manuscript. Availability of data and materials Patient identifiers were provided by The Danish Health Data Authority and data were extracted from the Danish National ...
Consistent with this interpretation, we found that the ability of anti-cancer drug etoposide to promote apoptosis, was reduced by WT-HCMV infection but not by ΔDUB-HCMV infection (Figure 3d). Next, we tested uptake of glucose, as cancer cells require increased glucose for metabolism and ...
Thus, it is possible that lower antibody titers reflect a less active immune response to HCMV among patients with brain metastases and that this may predict a poor outcome, but the primary diagnosis may also influence this interpretation. Thus, patients who respond to emerging HCMV activity with...
Moreover, the subjective interpretation of data could influence the findings, particularly given that certain advanced diagnostic investigations that might provide more detailed insights into the patient’s condition were not performed due to case-specific constraints. Despite these limitations, the study...
Test code(s) 10600X, 34179X This FAQ is provided for informational purposes only and is not intended as medical advice. A clinician’s test selection and interpretation, diagnosis, and patient management decisions should be based on his/her education, clinical expertise, and assessment of the pa...