Methods We calculated each patient's CMV viral load kinetics (mean, peak, maximum change, percentage of positive viral loads) from samples collected during the first five weeks after randomization and analyzed their value as surrogates for CMV disease by 24 weeks after randomization. First, we ...
[4].Green ML, Leisenring W, Xie H, et al. Cytomegalovirus viral load and mortality after haemopoietic stem cell transplantation in the era of pre-emptive therapy: a retrospective cohort study. Lancet Haematol. 2016;3(3):e119-e127. doi:10.1016/S2352-3026(15)00289-6 [5].Teira P, Batti...
2.Green ML, et al. Cytomegalovirus viral load and mortality after haemopoietic stem cell transplantation in the era of pre-emptive therapy: a retrospective cohort study. Lancet Haematol 2016 Mar;3(3):e119-27. 3.Tomblyn M, et al. Bio...
Viral-load kinetics and CMV disease - Reply Comment on Lancet. 2000 Jun 10;355(9220):2032-6. VC Emery,CA Sabin,AF Hassan-Walker,... - 《Lancet》 被引量: 4发表: 2000年 Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation ...
real-time PCR assay that amplifies cytomegalovirus (CMV) and human DNA in the same reaction tube, allowing for a viral load determination that is normaliz... JL Sanchez,GA Storch - 《Journal of Clinical Microbiology》 被引量: 343发表: 2002年 Quantification of Human Cytomegalovirus DNA by Real...
Studies concerning the effect of non-surgical periodontal therapy on the viral load are scarce. Here we aimed to determine the effect of non-surgical periodontal therapy on the viral load in chronic periodontitis patients. The present study aims to identify and compare the levels of Herpes Simplex...
METHODS:Sequential PMNL and plasma samples were analysed for determination of the CMV viral load using non-molecular methods and a quantitative polymerase chain reaction (PCR) assay. Screening of the same samples for the most common mutations conferring ganciclovir resistance was performed using nested...
CMV load in the initial phase of active infection and the rate of increase in viral load both correlate with CMV disease in transplant recipients; in ... VC Emery,CA Sabin,AV Cope,... - 《Lancet》 被引量: 1236发表: 2000年 Application of viral-load kinetics to identify patients who deve...
In addition, recipients of TCD HCT with persistent CMV infection, and higher viral load over time (Supplemental Figure 1), had significantly higher percentages of NKG2C+ NK cells compared with patients without persistent CMV infection (P = .01; Figure 1D). Together, these findings indicate that...
Real-time PCR (qPCR) was used to determine the viral load during active CMV infection and antiviral treatment. Results Sixty-three allogeneic HSCT recipients were prospectively evaluated; 49/63 (78%) patients were infected with CMV genotypes – gB1 19/49 (39%), gB2 17/49 (35%), gB3 3/...