这个基因的产物是检查点激酶1的一个重要上游调节因子,并触发细胞周期的检查点阻滞,以应对复制应激或dna损伤。在正常的s期,这种蛋白质也是有效的dna复制所必需的。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供,2010年6月] The product of this gene is an essential upstream regulator of checkpoint kinase...
Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] [中文简述(自动翻译):] 这个基因的产物是检查点激酶1的主要上游调节并触发细胞周期检查点阻滞响应于复制胁迫或DNA损伤。在一个正常的S相也需要有效的DNA复制的蛋白质。已发现该基因编码不同...
Germline alterations in the CLSPN gene in breast cancer families. Cancer Lett. 2008; 261 :93–97. doi: 10.1016/j.canlet.2007.11.003. [ Cross Ref ]Hannele Erkko, Katri Pylks, Sanna-Maria Karppinen, and Robert Winqvist. Germline alterations in the clspn gene in breast cancer families. ...
Gene Name: CLSPN Protein Name: Claspin (hClaspin) Human Gene Id: 63967 Swiss-Prot: Q9HAW4 Formulation: Liquid in PBS containing 50% glycerol, and 002% sodium azide Source: Rabbit Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specifi...
Human CLSPN shRNA Plasmid的详细介绍 shRNA Plasmid to inhibit CLSPN expression by RNA interference. This product contains 3 separate slightly different shRNA sequences which knock down human CLSPN gene specifically. Each vial contains 50 μg of lyophilized shRNA. ...
GeneCLSPN Long Gene namecapsin Synonyms Gene namecapsin同源物(爪蟾属)GenBank acessionAF297866 locs14.3 Discovery year2002-11-15 Pubmed identification1109062212766152 RefSeq identityNM 022111 Havana BLAST/blattothumg0000004168 mesh Data 编号05.478.566.350.170E05.478.566.380.360E05.478.583.400.17 ...
of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. ...
Attempts have been made to obtain insight into the role of CLSPN gene polymorphisms in oral cancer through the analysis of this study. We demonstrated that the OSCC risk of individuals with four CLSPN SNPs relative to the wild type did not differ significantly from that of the wild type when...
PROBLEM TO BE SOLVED: To provide a method by which psychiatric disorder can readily and accurately be inspected by using a new marker gene, and to provide a method by which a causative factor of the psychiatric disorder and a component of a therapeutic agent are identified by using the ...
380: Characterization of CpG islands and methylation status of Claspin gene (CLSPN) promoter - European Journal of Cancerdoi:10.1016/S0959-8049(14)50338-3Azenha, D.Lopes, C.Martins, T.C.Elsevier LtdEuropean Journal of Cancer