艾普蒂生物 通过研究CLPP的结构和功能,我们可以更好地理解细胞生物学的基本机制,并为疾病治疗提供新的思路和策略。参考文献:1. Liu, Y., Yang, M., & Lu, S. (2019). Mechanisms regulating turnover of ClpP protease in mycobacteria. Current Genetics, 65(1), 141-145.2. Carneiro, J., et al. (2...
Human caseinolytic protease P (HsClpP), an ATP-dependent unfolding peptidase protein in the mitochondrial matrix, controls protein quality, regulates mitochondrial metabolism, and maintains the integrity and enzyme activity of the mitochondrial respiratory chain (RC). Studies show that abnormalities in ...
英文名称: Human Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial/CLPP kit 用途: 用于科研实验,不得用于临床 产地: 上海 品牌: 梵态生物 包装规格: 96T 1800元/48T 1200元 标记物: 咨询客服 样本: 血清,血浆,细胞,组织,等相关液体 检测方法: 酶联免疫法 应用: 定量/定性/...
The caseinolytic protease P (ClpP) is a tetradecameric serine protease comprised of two heptameric rings stacked together in a cylindrical structure. It is one of the main proteolytic complexes in bacteria1. It associates with hexameric unfoldase chaperones of the AAA+ (ATPases Associated with d...
Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene. FEBS Lett 1995;377:249-52.Bross, P., Andresen, B.S., Knudsen, I., Kruse, T.A., and Gre- gersen, N. (1995). Human ClpP protease: cDNA sequence, tissue-specific expression and ...
人线粒体假定ATP依赖Clp蛋白酶水解蛋白亚基(CLPP)elisa试剂盒 品牌:白益生物 英文名称:HumanPutativeATP-dependentClpproteaseproteolyticsubunit,mitochondrial/CLPPkit 货号:BYP37216R 检测范围:0.3125-10ng/mL 本
Gersch M, Famulla K, Dahmen M, Go篓 bl C, Malik I, Richter K, Korotkov VS, Sass P, Ru篓 bsamen-Schaeff H, Madl T et al.: AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control. Nat Commun 2015, 6. This study analyzes the effects of ADEPs on...
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1. Cole, A., et al., Inhibition of theMitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute MyeloidLeukemia. Cancer Cell, 2015.27(6):p. 864-76. 2. Ishizawa,J., et al., Mitochondrial ClpP-Mediated Proteolysis Induces Selective CancerCell Lethality. Cancer Cell, 2019.35(5):...