Testing is initially completed at one-week intervals but is expanded to two-week intervals at six months, and then four-week intervals at twelve months if lab results have been within an appropriate range. Monitoring parameters may change if there is any break in therapy. In Canada, the ...
The CRISP trial results highlight that clozapine’s actions may be altered during MS such that people with progressive MS have an enhanced sensitivity to clozapine. Due to the early withdrawal of all participants in the clozapine group, this trial could not determine whether clozapine was able to...
The phrase “calibration and control materials” refers to any standard or reference material containing a known amount of a drug to be measured. The concentration of drug is calculated by comparing the results obtained for the unknown specimen with the results obtained for the standard. This is ...
The second of the replicate studies is presented in the Results section. Activity was evaluated in transparent (47.6 Â 25.4 Â 20.6 cm3 high) polystyrene enclosures using a computerized photobeam system (MotorMonitor Kinder Scientific). Animals were placed in the enclosures 20 min after drug ...
Prevalence of Constipation on Clozapine Full details of the meta-analysis results are summarized in Table 1. It was possible to pool data from 32 studies to establish that the point prevalence of clozapine-associated-constipation (n = 2013) was 31.2% (95% CI: 25.6–37.4, I2 = 84%, 32 ...