In 2008, it was used to treat only 4.4% of patients with schizophrenia in the U.S., which is ~10-20% of those with approved indications for clozapine for which there is no alternative of equal efficacy. Its use is much higher in Scandinavian countries and China. The primary indications ...
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The authors conducted a review of studies that highlighted its historical aspect, the mechanism of action, efficacy, tolerability, and indications of clozapine in current perspective.doi:10.5958/2394-2061.2015.00001.4Sekh Afrar Alam... SA Alam,A Baruah,B Timungpi - 《Dysphrenia》 被引量: 1发表...
Use caution when administering CLOZARIL to patients with a history of seizures or other predisposing risk factors for seizure (e.g., headtraumaor other CNSpathology, use of medications that lower the seizure threshold, or alcohol abuse). Because of the substantial risk of seizure associated with...
Its use is much higher in Scandinavian countries and China. The primary indications for clozapine are: 1) treatment-resistant schizophrenia or schizoaffective disorder, defined as persistent moderate to severe delusions or hallucinations despite two or more clinical trials with other antipsychotic drugs...
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Next, using a highly-structured decision tree, the nurse practitioner and psychiatrist assessed whether the remaining patients had an indication for this drug. Indications were treatment-resistant positive symptoms, tardive dyskinesia, aggression and suicidality. The severity of positive symptoms was ...
Indications:Thisproductisnotonlyeffectiveagainst psychoticpositivesymptoms,butalsohasnegativeeffectson negativesymptoms.Applicabletoacuteandchronic schizophreniaofvarioussubtypes,hallucinations,delusions, youthtypeofgoodresults.Itcanalsoreduceemotional symptomsassociatedwithschizophrenia(suchasdepression, guilt,anxiety).For...
Collaborate with other interprofessional healthcare team members, such as pharmacists and laboratory staff, to ensure the safe and effective use of clozapine. Indications Clozapine is an FDA-approved atypical antipsychotic drug for treatment-resistant schizophrenia.[1]The definition of treatment-resistant ...
In the second part, we offer procedures for selecting individuals for clozapine therapy based on proper indications and contraindications for treatment. We also include requirements regarding informed consent, dosage and special laboratory and clinical monitoring....