Clozapine [*administration & dosage, adverse effects, supply & distribution]Psychotic Disorders [diagnosis, drug therapy]Schizophrenia [*drug therapy]Background: Schizophrenia and related disorders such as schizophreniform and schizoaffective disorder are serious mental illnesses characterised by profound ...
Disturbances of movement mark catatonic-type schizophrenia. People with this type of schizophrenia may vary between extremes: they may remain immobile or may move all over the place. They may say nothing for hours, or they may repeat everything you say or do. These behaviors put these people ...
However, from one-third to two thirds of schizophrenia patients still have persistent 'positive' symptoms despite adequate dosage and duration of clozapine monotherapy.Among treatment-resistant schizophrenia patients with poor response to an adequate trial of clozapine monotherapy, 30-50% are treated ...
Clozapine has been used in some special groups of patients, including patients with severe borderline personality disorder (8), patients with aggressive schizophrenia (9), and mentally retarded adults (10). Of 12 in-patients with borderline personality disorder treated with clozapine for 16 weeks, ...
Clozapine is commonly used for the following mental health conditions. Schizophrenia Schizoaffective disorder Clozapine may also be used for other conditions as determined by your health care provider. How does clozapine work (mechanism of action)?
lithium, high-dose benzodiazepines, and electroconvulsive therapy. Clozapine currently appears to be the most effective antipsychotic for treatment-resistant schizophrenia and, but for its associated risk of agranulocytosis, should probably be regarded as the drug of first choice for the majority of ...
It is used to treat schizophrenia. It is used to treat problems with how one acts. It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take Clozapine Orally Disintegrating Tablets?
The patterns of clozapine use in New Zealand have been studied in 2796 patients with schizophrenia, of whom 917 (33%) were given clozapine, at a mean dosage of 372 mg/day and an average duration of illness of 9.7 years before starting clozapine (68c). Patients who had started treatment ...
This neuroleptic drug is mainly prescribed for treatment-resistant schizophrenia. In clozapine-naive subjects, orthostatic hypotension, bradycardia and syncope have been reported with a single 25 mg oral dose. Serum clozapine concentrations of the 3 cases were below the defined therapeutic range (350–...
Reducing suicidal behavior in patients with schizophrenia or schizoaffective disorder. Efficacy was established in an active- controlled study (1.2, 14.2). Clozapine Orally Disintegrating Tablet Dosage and Administration Starting Dose: 12.5 mg once daily or twice daily (2.3). Use cautious titration an...