Clozapine (Clozaril, Fazacio ODT, Versacloz) is a medication prescribed for the treatment of psychotic disorders including schizophrenia. Read about side effects, dosage, drug interaction, pregnancy and breastfeeding information.
Introduced in the US in 1990. clozapine was initially linked or ‘bundled’ with a proprietary drug monitoring and distribution system, the Clozaril® Patient Monitoring System (CPMS). This arrangement, unique in US pharmaceutical history, was held to be largely responsible for the high cost of...
Dosage and Administration Clozapine may be administered orally or intramuscularly. The manufacturer recommends initiation of clozapine therapy with 25 to 75 mg/day administered in 2 or 3 divided doses, followed by titration in 25 to 50 mg/day increments to achieve a target dose of 300 to 450 ...
Dosage forms and strengths 50 mg/mL oral suspension 25 mg, 50 mg, 100 mg, 200 mg oral tablets 12.5 mg, 25 mg, 100 mg, 150 mg, 200 mg orally disintegrating tablets How should I store clozapine? Oral Tablet.Clozapine oral tablet should be stored at a temperature not to exceed 86 F ...
Her symptom profile before clozapine treatment was characterized by positive symptoms: paranoid delusions, hallucinations, impulsive behaviour and anxiety. First rCBF SPECT-HMPAO study showed hypoactivity in right temporal lobe. Second SPECT evaluation was performed after four years during which the patient...
Two additional cases of stuttering have emerged; the first, in a 40-year-old man started to stutter when his clozapine dosage was increased from 400 mg/day; it was also associated with a marked increase in seizure activity (86A). The other case was in a 44-year-old man whose clozapine...
During the process, participants are required to maintain the original clozapine treatment, and adjust the dosage of clozapine according to the needs of the condition, but it must be ensured that between 300 mg and 600mg/day. Other antipsychotic drugs, antidepressants, and mood stabilizers were ...
Dosage could be reduced to 200 mg/d for clozapine or 4 mg/d for haloperidol in response to adverse effects. The only other psychotropic medication allowed was lorazepam after the first week. Medication was dispensed labeled with day of the week and morning (AM) or afternoon (PM). Patients ...
Dosage for Fazaclo Required Laboratory Testing Prior To Initiation And During Therapy Prior to initiating treatment with FAZACLO, a baseline ANC must be obtained. The baseline ANC must be at least 1500/μL for the general population, and at least 1000/μL for patients with documented Benign Et...
Beck Depression Inventory score was found as 38, and Beck Anxiety Scale score was found to be 22. The patient was treated with a dosage of 30 mg/d due to the diagnosis of major depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; the ...