Diagnosis of CLL revisited: increased specificity by a modified five-marker scoring system including CD200.doi:10.1111/bjh.14901The modified Matutes score has been the basis for the diagnosis of chronic lymphocytic leukaemia (CLL) by flow cytometry for the past 15 years. To increase the ...
Keywords chroniclymphocyticleukemia;CLLflowscoresystem;flowcytometry;CD200 B 细胞慢性淋巴细胞增 殖性疾病(Bcellchro- niclymphoproliferativedisorders,B-CLPD)是一 组在形态学和免疫表型特征以及临床行为上均有 异质性的疾病 .[1] 由于不同疾病类别的临床演变 和治疗反应可 能不同,因此正确的诊断至关重要. 流...
Response assessment after FCR therapy included routine clinical and laboratory assessments, radiographic imaging of CLL manifestations (used method at the discretion of the local investigator), and flow cytometry for minimal residual disease (MRD) assessment. The latter was performed using four-color ...
The expression of CD38 and ZAP-70 was examined in a cohort of 56 patients with CLL by flow cytometry, with a cut-off positivity value of 20% and higher and 10% and higher, respectively (Table 1). The cut-off values were experimentally defined as functional thresholds (ie, values below ...