HFpEF are more commonly female, show higher SBP at the presentation (p<0,001), and have more non-cardiac comorbidities, such as renal dysfunction (p<0,001), anemia (p=0,05), chronic obstructive pulmonary disease (p=0,036) and also atrial fibrillation (p=0,04); in this group ...
and current guidelines indicate that invasive endomyocardial biopsy is the gold standard to diagnose and monitor organ rejection. Ideally, graft rejection may be diagnosed and predicted by noninvasive biomarkers present in the peripheral blood or other biological fluids [99]. Specifically,...
but HFpEF and HFrEF shared similar clinical characteristics, comorbidities, echocardiographic findings, laboratory data, and even on-discharge medications, with some significant but small absolute differences. The on-discharge prescription of the 3 guidelines-recommended ...
performed LSM using ultrasound 2D-SWE on discharge in 80 acute decompensated HFpEF patients [64]. Patients with higher LSM (>10.2 kPa) had worse outcomes after a median follow-up of 212 days, with LSM identified as an independent risk factor for composite endpoints (all-cause death; ...
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of ...
Reader feedback on LGE pre-ICDs, PFA for AF ablation, CTO-PCI, endovascular ablation of the greater splanchnic nerve in HFpEF, and data sharing are the topics John Mandrola, MD, covers this week. Lifestyle Medicine: Not Just for the Wealthy ...
[27]. Furthermore, precise risk prediction models tailored for HFpEF and HFrEF have been developed [28]. The HFpEF-specific model included age, sex, systolic BP, BMI, antihypertensive treatment and previous myocardial infarction (MI), while the HFrEF-specific model additionally included smoking, ...
Guidelines recommend empagliflozin or dapagliflozin in patients with T2DM and LVEF > 40% (HF with mildly reduced EF and HFpEF) to reduce the risk of HF hospitalization or CV death6,10. However, SGLT2 inhibitors are more expensive than traditional treatments. Guidelines recommend that DM ...
Kerendia has been recommended for adults with CKD associated with T2D in several major treatment guidelines, including the American Diabetes Association®(ADA), the American Association of Clinical Endocrinology®, and the Kidney Disease: Improving Global Outcomes...
These models of systemic pressure overload have been used to study several aspects of HFpEF in both young and importantly, old dogs, given the significant aging component associated with this type of HF (45). Use of the “Page model” of bilateral renal wrapping for 6 to 12 weeks (both ...