While Vps10p follows a direct pathway between the TGN and the late endosome/prevacuolar compartment (PVC), Kex2p partitions between this pathway and an indirect pathway through the early endosome. Using cell-free reconstitution of TGN-PVC transport [Abazeed, M.E., et al. (2005) 280:4442鈥 ...
Extracellular matrixHormone receptorsThe hormone prolactin promotes lactational differentiation of mammary epithelial cells (MECs) via its cognate receptor and the downstream JAK2-STAT5a signalling pathway. In turn this regulates transcription of milk protein genes. Prolactin signalling depends on a cross-...
bovis invasion into cells, chlorpromazine (CPZ), amiloride (AMI), and methyl-β-cyclodextrin (M-β-CD) were used to inhibit CLR-mediated clathrin-dependent endocytosis (CDE) pathway, macropinocytosis, and lipid raft pathway, respectively. Subsequently, the invasion rates of PG45 into these four ...
‘EGF (epidermal growth factor) receptor pathway substrate clone no. 15’] contains three copies of EHdomains, which interact with NPF motif-containing proteins including Epsin, AP180/CALM, Numb and Esc1. The central coiled-coil region allows the protein to form homo-oligomers (dimers and tetr...
The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin. Proc Natl Acad Sci USA 2005; 102: 2766–2771. Article CAS PubMed PubMed Central Google Scholar Antonin W, Holroyd C, Fasshauer D, Pabst S, Von Mollard GF...
Deubiquitination Step in the Endocytic Pathway of Yeast Plasma Membrane Proteins: Crucial Role of Doa4p Ubiquitin Isopeptidase The Fur4p uracil permease, like most yeast plasma membrane proteins, undergoes ubiquitin-dependent endocytosis and is then targeted to the vacuole (equival... S Dupré,R Hag...
The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin. Proc Natl Acad Sci USA 2005; 102: 2766–2771. Article CAS PubMed PubMed Central Google Scholar Antonin W, Holroyd C, Fasshauer D, Pabst S, Von Mollard GF...
In the present work, to better understand how avian-origin CoVs may be transmitted to pigs, we investigated the unknown DCoV entry pathway in avian cells. We show that clathrin-mediated endocytosis is involved in the entry of these DCoV pseudoviruses into chicken-origin DF-1 cells. ...
1B, treat- ment of cells by genistein (100 µg/ml) or herbimycin A (1 µM) had no influence on FcαR endocytosis, suggesting that tyrosine kinase activity was not required for FcαR endocytosis and further indicating that the endocytosis was mediated by a clathrin-dependent pathway. ...
These findings demonstrate that HTN enters cells via the clathrin-coated pit pathway and uses low-pH-dependent intracellular compartments for infectious entry. 展开 关键词: Hantaan virus entry clathrin-dependent endocytosis endosome DOI: 10.1006/viro.2001.1303 被引量: 307 ...