Iron is essential for living cells. Uptake of iron-loaded transferrin by the transferrin receptor 1 (CD71, TFR) is a major but not sufficient mechanism and an alternative iron-loaded ligand for CD71 has been assumed. Here, we demonstrate that CD71 utiliz
we asked whether chimeric LDLRAD3, where the native D1 domain is replaced by the CR5 domain of LDLR, can serve as a GETV receptor. Similarly, we investigated if the reciprocal swap would enable VEEV to use chimeric LDLR as a receptor. It was found that the chimeric receptors were expres...
Clathrin is required for Scar/Wave-mediated lamellipodium formation. J. Cell Sci. 124, 3414-3427.Gautier, J. J., Lomakina, M. E., Bouslama-Oue... JJ Gautier,ME Lomakina,L Bouslama-Oueghlani,... - 《Journal of Cell Science》 ...
Once internalized, beta-arrestin1 is rephosphorylated. Thus, as with the classical endocytic adaptor protein complex AP2, beta-arrestin1 functions as a clathrin adaptor in receptor endocytosis which is regulated by dephosphorylation at the plasma membrane. 展开 ...
et al. (2001) The huntingtin interacting protein HIP1 is a clathrin and alpha- adaptin-binding protein involved in receptor-mediated endocytosis. Hum. Mol. Genet., 10, 1807-1817.Waelter S, Scherzinger E, Hasenbank R, et al: The huntingtin interacting protein HIP1 is a clathrin and alpha...
We have identified E-cadherin as the first cellular receptor involved in entry of a gram-positive bacterium into epithelial cells. E-cadherin binds to L. monocytogenes internalin, which represents a new ligand for cadherin heterophilic interactions. This finding has implications in the understanding ...
the strong inhibition of endocytosis in mitosis of CD8 chimeras containing any of the three major internalization motifs for clathrin-mediated endocytosis (YXXΦ, [DE]XXXL[LI], or FXNPXY) or a CD8 protein with the cytoplasmic tail of the cation-independent mannose 6-phosphate receptor...
展开 关键词: CORTICAL ACTIN CYTOSKELETON MAP KINASE PATHWAY A-FACTOR RECEPTOR SACCHAROMYCES-CEREVISIAE INTEGRITY PATHWAY PLASMA-MEMBRANE SECRETORY PATH PROTEIN UBIQUITIN CLATHRIN DOI: 10.1017/S0021859601008541 被引量: 100 年份: 2007 收藏 引用 批量引用 报错 分享 全部...
Crimean-Congo hemorrhagic fever virus (CCHFV) is the most widespread tick-born zoonotic bunyavirus that causes severe hemorrhagic fever and death in humans. CCHFV enters the cell via clathrin-mediated endocytosis which is dependent on its surface glycopr
between λ2 and β1 integrins also facilitate reovirus internalization by recruiting clathrin for endocytosis, at least in some cell types20,29,30. CHO cells used for ectopic expression of PirB do not express σ1 receptors. Reovirus efficiently binds and infects PirB-expressing CHO cells, ...