The arrival of a great number of new antineoplastic agents has made it necessary to reclassify all of them. Anticancer drugs may act at different levels: cancer cells, endothelium, extracellular matrix, the immune system or host cells. The tumour cell can be targeted at the DNA, RNA or prote...
The arrival of a great number of new antineoplastic agents has made it necessary to reclassify all of them. Anticancer drugs may act at different levels: cancer cells, endothelium, extracellular matrix, the immune system or host cells. The tumour cell can be targeted at the DNA, RNA or prote...
Classification of anticancer drugs--a new system based on therapeutic targets. Cancer Treat. Rev. 29, 515-523 (2003). 58Espinosa E, Zamora P, Feliu J, et al. Classification of anticancer drugs-a new system based on thera- peutic targets. Cancer Treat Rev 2003;29(6):515-23....
PLS-DA) indicated that in comparison with the control group, the media amino-acid consumption profiling can distinguish the two anticancer drugs with different mechanisms, which provides a new perspective for the pre-classification of drug action mechanisms during the screening of new anticancer drugs...
Machine learning methods trained on cancer cell line panels are intensively studied for the prediction of optimal anti-cancer therapies. While classification approaches distinguish effective from ineffective drugs, regression approaches aim to quantify the degree of drug effectiveness. However, the high spec...
Antimetabolites are a class of anticancer drugs that work by interfering with DNA synthesis to kill cancer cells. 5-fluorouracil (5-FU), capecitabine, floxuridine, cytarabine, gemcitabine, decitabine, and vidaza are some of the most important medications in this class. These compounds are pyrimidine...
drugs with different mechanisms, which provides a new perspective for thepre-classificationofdrugaction mechanisms during the screening of new anticancer drugs. chrom-china.com chrom-china.com 以相对峰面积作为原始数据,通过Matlab7.1软件平台,用偏最小二乘判别分析(PLS-DA)得分图 进行关联研究,结果表明: ...
12.Study on Biological Characterization, Pharmacokinetics and Efficacy of Anticancer Drug as Liver-target Nanoparticles;肝靶向纳米制剂的生物特性及药动、药效学研究 13.An agent that kills germs, especially pathogenic microorganisms;a disinfectant.杀菌剂一种杀死细菌的药剂,尤指致病的微生物;杀虫剂 14.an alk...
However, the types of administration could be very different. 2.2. Oral Administration The most used and conventional method for the administration and the delivery of drugs is the oral delivery system. This is performed to delivery drugs in solid form, generally powder, but, in some cases, it...
NPs are used as carriers for some approved anticancer drugs to the site of cancer with minimum effect on normal tissue and increasing the drug bioavailability and protect it from its breakdown in stomach media in addition to increasing its the pharmacokinetic and pharmacological properties. NPs are ...