Table 1. Types of anti-cancer drugsLewandowski, Clare M
These results demonstrate that eATP induces different types of drug resistance by eATP internalization and iATP elevation, implicating the ATP-rich tumor microenvironment in cancer drug resistance, expanding our understanding of the roles of eATP in the Warburg effect and offering new anticancer drug ...
of certain diseases, includingcancer, wheretumourcells thrive in hypoxia. Someanticancer drugstargeting HIF have proven successful in slowing or halting tumour growth. The discovery of how cells sense and adapt to reduced oxygen levels formed the basis of the 2019Nobel Prizefor Physiology or Medicine...
simmunedefenses, marrow transplants have been used to treat certain types ofimmune deficiencyand hematological disorders, especiallyleukemia. The sensitivity of marrow to damage byradiation therapyand some anticancer drugs accounts for the tendency of these treatments to impair immunity and blood ...
aP-gp knockout mice has demonstrated the role of P-gp in multidrug resistance and bioavailability of paclitaxel and other anticancer drugs. P-gp击倒老鼠展示了P-gp的paclitaxel和其他抗癌药物的角色在multidrug抵抗和生物相容性。 [translate] aThe penetration of the fluid phase of the ink was then ...
We further employed "pRRophetic" to investigate differences in IC50 expression of chemotherapy medicines between low-risk and high-risk cohorts (Fig. 8A). Our findings revealed that LUAD in the high-risk cohort presented decreased IC50 values of anticancer drugs such as AICAR, AKT.inhibitor.VIII...
Recent US Food and Drug Administration warnings on hepatitis B reactivation with immune-suppressing and anticancer drugs: just the tip of the iceberg? Hepatology 2015;61:703-711. 56. Kim HN, Harrington RD, Shuhart MC, et al. Hepatitis C virus activation in HIV-infected patients initiating ...
Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents. testing their ability to inhibit the proliferation of human umbilical vein endothelial cells (HUVECs), cord formation and migration in response to ... AH Abadi,SM Abou-...
to incorporating socio-economic and technological dimensions.Nanocomplexes systems composed natural poylymers have actually pharmacotechnical benefitsTAK-875such as for example increase of water solubility and a decrease of drugs poisoning. Amphotericin B (AmB) is a drug apply as anti-leishmanial and ...
and to distinguish cytostatic versus cytocidal potential of anticancer drugs on malignant cell growth. We offer a convenient ATP Determination Kit (A22066) for the sensitive bioluminescence-based detection of ATP with recombinant...