TheClassificationofAnticancerDrugs Accordingtochemicalstructureandresourceofthedrug;Accordingtobiochemistrymechanismsofanticanceraction;Accordingtothecycleorphasespecificityofthedrug TheClassificationofAnticancerDrugs Accordingtochemicalstructureandresourceofthedrug:
ClassificationSelectivityMitochondria have emerged as an intriguing target for anti-cancer drugs, inherent to vast majority if not all types of tumours. Drugs that target mitochondria and exert anti-cancer activity have become a focus of recent research due to their great clinical potential (which ...
Table 1. Classification of anticancer drugs.⁎ Pharmaceutical familyExamplesMechanism of actionReference Alkylating Agents Altretamine, Bendamustine, Busulfan, Carmustine, Chlorambucil, Cyclophosphamide, Dacarbazine, Ifosfamide, Lomustine, Mechlorethamine, Melphalan, Procarbazine, Streptozocin, Temozolomide, Thiot...
Embryonic Carcinoma of Testis 60~80% Note:* Combination with other therapeutics **Chemotherapy Level of our country is high The Classification of Anticancer Drugs ? According to chemical structure and resource of the drug; According to biochemistry mechanisms of anticancer action; According to the ...
(ChorionEpithelioma)**80~90% SeminomaofTestis**60~90% EmbryonicCarcinomaofTestis60~80%Note:*Combinationwithothertherapeutics**ChemotherapyLevelofourcountryishighTheClassificationofAnticancerDrugs AccordingtochemicalstructureandAccordingtochemicalstructureandresourceofthedrug;; AccordingtoAccordingtobiochemistry...
Rat GST-P (GST 7-7) and human GST-pi, both of which belong to Class pi in the species-independent classification of GST, have been known as a marker enzyme for rat and human (pre) neoplastic lesions, respectively. GST-P is increased in rat hepatic preneoplastic foci resistant to ...
The DNA damage response and cancer therapy. Genomic instability is one of the most pervasive characteristics of tumour cells and is probably the combined effect of DNA damage, tumour-specific DNA rep... CJ Lord,A Ashworth - 《Nature》
Moreover, when combining this capability with our novel drug sensitivity measure that is comparable across drugs, we can leverage the full potential of SAURON-RF and ultimately perform drug prioritization: we can first identify effective drugs (classification) and then rank them by their predicted ...
Tanabe, K.et al.Comprehensive serum glycopeptide spectra analysis combined with artificial intelligence (CSGSA-AI) to diagnose early-stage ovarian cancer.Cancers12(9), 2373 (2020). Buturović, L. & Miljković, D.A novel method for classification of tabular data using convolutional neural networ...
The NCI classification of the 4 degrees of QT prolongation associated with anticancer drugs is as follows: grade 1, QTc 450–480 ms; grade 2, QTc 481–500 ms; grade 3 QTc > 501 ms on at least two separate electrocardiograms; grade 4 QTc > 501 ms or a change of >...