Anticancer drugsPharmacological classificationThe combination of chromatography and chemometrics has been introduced in order to provide information about drug analytes, biological macromolecules, the stationary phase, whose properties are related to molecular pharmacology and rational drug design. In this work ...
Therefore, it is obvious that the bioactivity of various anticancer drugs is associated with their ability to penetrate the membrane lipid structure. Thus, their conjugation with fatty acids shows multifaceted effects [[26], [27], [28]]. In the up-to-date literature there are no evidences ...
The use of oral anticancer drugs has increased during the last decade, because of patient preference, lower costs, proven efficacy, lack of infusion-related inconveniences, and the opportunity to develop chronic treatment regimens. Oral administration of anticancer drugs is, however, often hampered b...
Anti-angiogenesis drugs can inhibit the development and growth of breast cancer and lead to its ischemic death [13]. Mounting studies showed that the monoclonal antibody drugs had a significant anticancer effect and could improve the survival ability of patients. However, these agents were only ...
Liu, Ph.D, Department of Pharmacology and Molecular S More Citation: Shim JS, Liu JO. Recent Advances in Drug Repositioning for the Discovery of New Anticancer Drugs. Int J Biol Sci 2014; 10(7):654-663. doi:10.7150/ijbs.9224. https://www.ijbs.com/v10p0654.htm Copy Other styles ...
Prevalence, classification, and mechanism of potential drug interactions. aPotential drug-drug interactions. Full size image Potential drug–drug interactions involving anticancer drugs and supportive care agents are listed in Table 3. As the variety of drug classes is diverse, only PDDIs with potentia...
Combination therapy has gained popularity in cancer treatment as it enhances the treatment efficacy and overcomes drug resistance. Although machine learning (ML) techniques have become an indispensable tool for discovering new drug combinations, the data
The Classification and Application of Toxic Chinese Materia Medica Many important drugs in the Chinese materia medica (CMM) are known to be toxic, and it has long been recognized in classical Chinese medical theory that to... X Liu,Q Wang,G Song,... - 《Phytotherapy Research Ptr》 被引量...
such as P-glycoprotein (P-gp/ABCB1), multidrug resistance-associated protein 1 (MRP1/ABCC1), and breast cancer resistance protein (BCRP/ABCG2), has been considered a pragmatic strategy for reinstating drug sensitivity in resistant cells when co-administered with anticancer drugs (Feyzizadeh et...
involved in cucurbitacin B's mechanism of action, which results in strong antitumor effects on a range of malignant tumors; in addition, cucurbitacin B can improve the drug resistance phenomenon of tumor therapy, and can play a synergistic effect when combined with various antitumor drugs [26]. ...