The editorial chairman of this revision is H. Yoshiji, and the deputy editorial chairman is S. Nagoshi; experts in each field contributed to the writing This revision was performed according to the Minds clinical practice guideline preparation manual, and the preparation was advanced so that it w...
Individual time within target range in patients treated with vitamin K antagonists: main determinant of quality of anticoagulation and predictor of clinical outcome. A retrospective study of 2300 consecutive patients with venous thromboembolism. Br. J. Haematol. 128, 513–519 (2005). Article PubMed ...
cirrhosis patients do not spontaneously bleed mostly due to the fact that there is a concomitant decrease in anticoagulant factors such as protein C, protein S and antithrombin III (attributed to decreased hepatocyte function, increased consumption due DIC or hyperfibrinolysis, and vitamin K deficiency...
Vitamin D deficiency is associ- ated with impaired muscle contractile function in the general population.(15) Although studies evaluating the role of vitamin D deficiency on frailty and sarco- penia in patients with cirrhosis are lacking, vitamin D deficiency is prevalent in patients with cirrhosis...
Generally, patients suffering from liver disease present vitamin deficiencies due to altered hepatic function, reduction of reserves, as well as inadequate dietary intake or malabsorption[187]. Deficiencies of vitamins and electrolytes can potentially cause a variety of neuropsychiatric symptoms, hence mimic...
Fig. 3. Effects of Vitamin D3 (VD3) treatments on hepatic placental glutathione-S-transferase (GST-P), and keratin (K)8/18 during diethylnitrosamine(DEN)/thioacetamide(TAA)-induced hepatocarcinogenesis. Representative photomicrographs depicting GST-P or K8/18 positive (+) and negative (-) foci...
> Section > Chapter Aboutwerat, A.; Pemberton, P.W.; Smith, A.; Burrows, P.C.; Mcmahon, R.F.T.; Jain, S.K.; Warnes, T.W. Biochimica et Biophysica Acta 1637(2): 142-150 2003 ISSN/ISBN:0006-3002 12633902 10.1016/s0925-4439(02)00225-9 ...
cirrhosis treatment with vitamin A-coupled liposomes carrying siRNA against heat shock protein 47reactive oxygen species (ROShepatic fibrosis and role of HSC and HSP47HSP47 - for maturation of procollagen molecules in ERrole of HSP47 in collagen production by HSCs...
Objectives: The goal of this study was to evaluate the effectiveness of intravenous (IV) vitamin K in cirrhosis. Methods: This was a retrospective study of cirrhotic patients, not on anticoagulation, with administration of IV vitamin K and a baseline INR > 1.5. The primary outcome was the ...
The available data on the influence of liver cirrhosis on vitamin K status in CF patients is scarce. Therefore, the aims of the present study were to assess the prevalence of vitamin K deficiency in cirrhotic CF subjects and to determine whether it correlates with liver cirrhosis.Krzyzanowska,...