Recently, circulating follicular helper T cells (cTfh) have been identified in peripheral blood; this facilitates the study of cTfh as potential biomarker in renal transplantation. With this background, the aims of our study are: (1) to show the capacity of cTfh to differentiate B ce...
circulating follicular helper T cellsCXCR5CXCR3–PD-1+Objectives: Which helper CD4+ T cell subset contributes to autoantibodies generation and severity of end-organ involvement in lupus patients remains to be explored. Our research aims to investigate the roles of circulating Tfh (cTfh) cell ...
Together, these data demonstrated that bacterial antigen stimulation is a potential source of aberrant Tfh cell activation in PBC patients. 展开 关键词: Primary biliary cholangitis Follicular helper T cells DOI: 10.1016/j.intimp.2017.08.004 被引量: 8 ...
This is the first in-depth characterization of ZEBOV-GP specific, circulating follicular T cells (cTfh). Since antibody titers correlated with protection in preclinical models of ZEBOV infection, Tfh were predicted to correlate with protection. Indeed, the ZEBOV-specific cTfh data correlated with ...
If that doesn't work, please contact support so we can address the problem. Abstract CD4+ CXCR5+ T cell in peripheral blood is known as circulating follicular helper T cell (Tfh), which can produce interleukin 21 (IL-21). In the current study, we investigated changes of circulating Tfh ...
Circulating T follicular helper (cTfh) cells have been identified as counterparts of germinal center Tfh (GC Tfh) cells in humans and can support T-dependent B cell maturation and antibody production in vitro. However, the role of cTfh cells in neutraliz
The frequency, phenotype and molecular function of different circulating B cell and T follicular helper cell (TFH) subsets were examined by flow cytometry. The function of the CD40/CD40?L interaction in immunoglobulin class-switch recombination (CSR) was evaluated by assessing the induction of ...
et al. Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19. Nat. Med. 26, 1428–1434 (2020). Welten, S. P. M., Redeker, A., Toes, R. E. M. & Arens, R. Viral persistence induces antibody inflation without altering antibody avidity. J. ...
Altered ratio of circulating follicular regulatory T cells and follicular helper T cells during primary EBV infectionAltered ratio of circulating follicular regulatory T cells and follicular helper T cells during primary EBV infectionInfectious mononucleosisEpstein...
follicular helper T (T FH ) cell that liaises first with the DC, before migrating to the B cell follicle for repeated interaction with B cells 1 . Such T FH cells bear a characteristic phenotype including expression of markers such as CXC-chemokine receptor 5 (CXCR5; which promotes homing ...